[71] Xanthogranulomatous pyelonephritis (XGP): A case report
Objective: To report on a case of xanthogranulomatous pyelonephritis (XGP) diagnosed as renal cell carcinoma (RCC) based on clinical and radiological findings. XGP is an uncommon form of chronic pyelonephritis. It is an inflammatory condition in which the renal parenchyma is invaded and replaced by...
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Taylor & Francis Group
2018
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/31be10adbb114e3484f7ab9428acc350 |
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| Sumario: | Objective: To report on a case of xanthogranulomatous pyelonephritis (XGP) diagnosed as renal cell carcinoma (RCC) based on clinical and radiological findings. XGP is an uncommon form of chronic pyelonephritis. It is an inflammatory condition in which the renal parenchyma is invaded and replaced by granulomatous tissue containing lipid-laden macrophages, also known as xanthoma cells. The aetiology is not well understood; however, most patients have underlying chronic inflammatory conditions such as recurrent urinary tract infections (UTIs), obstructive uropathies or renal calculi. The presenting symptoms are not specific, and its radiological findings closely resemble other pathological entities. Thus, a preoperative diagnosis is often difficult. Methods: This is a case of a 61-year-old woman who was referred to the Urology clinic at King Abdulaziz University Hospital from a polyclinic with ultrasonography (US) showing a mass in her right kidney. The patient only complained of vague abdominal pain, and on physical examination, she had mild tenderness in the right side of the abdomen. Laboratory results were normal. Results: The US of the kidney showed a large, complicated cystic mass, and a contrast-enhanced computed tomography scan showed a large exophytic cystic lesion (Bosniak III) in the characteristic claw sign. The management plan was to proceed with a radical nephrectomy. Conclusion: XGP should be given due consideration in the differential diagnosis of type III renal cystic disease. A preoperative diagnosis cannot always be made due to its nonspecific clinical presentation and radiological findings. |
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