[71] Xanthogranulomatous pyelonephritis (XGP): A case report

Objective: To report on a case of xanthogranulomatous pyelonephritis (XGP) diagnosed as renal cell carcinoma (RCC) based on clinical and radiological findings. XGP is an uncommon form of chronic pyelonephritis. It is an inflammatory condition in which the renal parenchyma is invaded and replaced by...

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Autores principales:	Budoor Salman, Alana Sunbol, Ehab Al Sayed, Mohammad Wazzan
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2018
Materias:	Diseases of the genitourinary system. Urology RC870-923
Acceso en línea:	https://doaj.org/article/31be10adbb114e3484f7ab9428acc350
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spelling	oai:doaj.org-article:31be10adbb114e3484f7ab9428acc3502021-12-02T08:22:58Z[71] Xanthogranulomatous pyelonephritis (XGP): A case report2090-598X10.1016/j.aju.2018.10.024https://doaj.org/article/31be10adbb114e3484f7ab9428acc3502018-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2090598X18301189https://doaj.org/toc/2090-598XObjective: To report on a case of xanthogranulomatous pyelonephritis (XGP) diagnosed as renal cell carcinoma (RCC) based on clinical and radiological findings. XGP is an uncommon form of chronic pyelonephritis. It is an inflammatory condition in which the renal parenchyma is invaded and replaced by granulomatous tissue containing lipid-laden macrophages, also known as xanthoma cells. The aetiology is not well understood; however, most patients have underlying chronic inflammatory conditions such as recurrent urinary tract infections (UTIs), obstructive uropathies or renal calculi. The presenting symptoms are not specific, and its radiological findings closely resemble other pathological entities. Thus, a preoperative diagnosis is often difficult. Methods: This is a case of a 61-year-old woman who was referred to the Urology clinic at King Abdulaziz University Hospital from a polyclinic with ultrasonography (US) showing a mass in her right kidney. The patient only complained of vague abdominal pain, and on physical examination, she had mild tenderness in the right side of the abdomen. Laboratory results were normal. Results: The US of the kidney showed a large, complicated cystic mass, and a contrast-enhanced computed tomography scan showed a large exophytic cystic lesion (Bosniak III) in the characteristic claw sign. The management plan was to proceed with a radical nephrectomy. Conclusion: XGP should be given due consideration in the differential diagnosis of type III renal cystic disease. A preoperative diagnosis cannot always be made due to its nonspecific clinical presentation and radiological findings.Budoor SalmanAlana SunbolEhab Al SayedMohammad WazzanTaylor & Francis GrouparticleDiseases of the genitourinary system. UrologyRC870-923ENArab Journal of Urology, Vol 16, Iss , Pp S34- (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the genitourinary system. Urology RC870-923
spellingShingle	Diseases of the genitourinary system. Urology RC870-923 Budoor Salman Alana Sunbol Ehab Al Sayed Mohammad Wazzan [71] Xanthogranulomatous pyelonephritis (XGP): A case report
description	Objective: To report on a case of xanthogranulomatous pyelonephritis (XGP) diagnosed as renal cell carcinoma (RCC) based on clinical and radiological findings. XGP is an uncommon form of chronic pyelonephritis. It is an inflammatory condition in which the renal parenchyma is invaded and replaced by granulomatous tissue containing lipid-laden macrophages, also known as xanthoma cells. The aetiology is not well understood; however, most patients have underlying chronic inflammatory conditions such as recurrent urinary tract infections (UTIs), obstructive uropathies or renal calculi. The presenting symptoms are not specific, and its radiological findings closely resemble other pathological entities. Thus, a preoperative diagnosis is often difficult. Methods: This is a case of a 61-year-old woman who was referred to the Urology clinic at King Abdulaziz University Hospital from a polyclinic with ultrasonography (US) showing a mass in her right kidney. The patient only complained of vague abdominal pain, and on physical examination, she had mild tenderness in the right side of the abdomen. Laboratory results were normal. Results: The US of the kidney showed a large, complicated cystic mass, and a contrast-enhanced computed tomography scan showed a large exophytic cystic lesion (Bosniak III) in the characteristic claw sign. The management plan was to proceed with a radical nephrectomy. Conclusion: XGP should be given due consideration in the differential diagnosis of type III renal cystic disease. A preoperative diagnosis cannot always be made due to its nonspecific clinical presentation and radiological findings.
format	article
author	Budoor Salman Alana Sunbol Ehab Al Sayed Mohammad Wazzan
author_facet	Budoor Salman Alana Sunbol Ehab Al Sayed Mohammad Wazzan
author_sort	Budoor Salman
title	[71] Xanthogranulomatous pyelonephritis (XGP): A case report
title_short	[71] Xanthogranulomatous pyelonephritis (XGP): A case report
title_full	[71] Xanthogranulomatous pyelonephritis (XGP): A case report
title_fullStr	[71] Xanthogranulomatous pyelonephritis (XGP): A case report
title_full_unstemmed	[71] Xanthogranulomatous pyelonephritis (XGP): A case report
title_sort	[71] xanthogranulomatous pyelonephritis (xgp): a case report
publisher	Taylor & Francis Group
publishDate	2018
url	https://doaj.org/article/31be10adbb114e3484f7ab9428acc350
work_keys_str_mv	AT budoorsalman 71xanthogranulomatouspyelonephritisxgpacasereport AT alanasunbol 71xanthogranulomatouspyelonephritisxgpacasereport AT ehabalsayed 71xanthogranulomatouspyelonephritisxgpacasereport AT mohammadwazzan 71xanthogranulomatouspyelonephritisxgpacasereport
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[71] Xanthogranulomatous pyelonephritis (XGP): A case report

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