The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant

The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant

Avian influenza A virus (IAV) strains replicate poorly in mammalian hosts, but mechanisms underlying species restriction are incompletely understood. Here, Bogdanow et al. show that avian and mammalian adapted IAV strains have evolved different RNA structure features for regulation of M segment RNA...

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Autores principales: Boris Bogdanow, Xi Wang, Katrin Eichelbaum, Anne Sadewasser, Immanuel Husic, Katharina Paki, Matthias Budt, Martha Hergeselle, Barbara Vetter, Jingyi Hou, Wei Chen, Lüder Wiebusch, Irmtraud M. Meyer, Thorsten Wolff, Matthias Selbach
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/31c5226fb8bf4e6b9bc945e1829498fd
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spelling oai:doaj.org-article:31c5226fb8bf4e6b9bc945e1829498fd2021-12-02T16:57:43ZThe dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant10.1038/s41467-019-13520-82041-1723https://doaj.org/article/31c5226fb8bf4e6b9bc945e1829498fd2019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13520-8https://doaj.org/toc/2041-1723Avian influenza A virus (IAV) strains replicate poorly in mammalian hosts, but mechanisms underlying species restriction are incompletely understood. Here, Bogdanow et al. show that avian and mammalian adapted IAV strains have evolved different RNA structure features for regulation of M segment RNA splicing.Boris BogdanowXi WangKatrin EichelbaumAnne SadewasserImmanuel HusicKatharina PakiMatthias BudtMartha HergeselleBarbara VetterJingyi HouWei ChenLüder WiebuschIrmtraud M. MeyerThorsten WolffMatthias SelbachNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Boris Bogdanow
Xi Wang
Katrin Eichelbaum
Anne Sadewasser
Immanuel Husic
Katharina Paki
Matthias Budt
Martha Hergeselle
Barbara Vetter
Jingyi Hou
Wei Chen
Lüder Wiebusch
Irmtraud M. Meyer
Thorsten Wolff
Matthias Selbach
The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant
description Avian influenza A virus (IAV) strains replicate poorly in mammalian hosts, but mechanisms underlying species restriction are incompletely understood. Here, Bogdanow et al. show that avian and mammalian adapted IAV strains have evolved different RNA structure features for regulation of M segment RNA splicing.
format article
author Boris Bogdanow
Xi Wang
Katrin Eichelbaum
Anne Sadewasser
Immanuel Husic
Katharina Paki
Matthias Budt
Martha Hergeselle
Barbara Vetter
Jingyi Hou
Wei Chen
Lüder Wiebusch
Irmtraud M. Meyer
Thorsten Wolff
Matthias Selbach
author_facet Boris Bogdanow
Xi Wang
Katrin Eichelbaum
Anne Sadewasser
Immanuel Husic
Katharina Paki
Matthias Budt
Martha Hergeselle
Barbara Vetter
Jingyi Hou
Wei Chen
Lüder Wiebusch
Irmtraud M. Meyer
Thorsten Wolff
Matthias Selbach
author_sort Boris Bogdanow
title The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant
title_short The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant
title_full The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant
title_fullStr The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant
title_full_unstemmed The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant
title_sort dynamic proteome of influenza a virus infection identifies m segment splicing as a host range determinant
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/31c5226fb8bf4e6b9bc945e1829498fd
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