A Comparative Proteomic Analysis of Extracellular Vesicles Associated With Lipotoxicity

A Comparative Proteomic Analysis of Extracellular Vesicles Associated With Lipotoxicity

Extracellular vesicles (EVs) are emerging mediators of intercellular communication in nonalcoholic steatohepatitis (NASH). Palmitate, a lipotoxic saturated fatty acid, activates hepatocellular endoplasmic reticulum stress, which has been demonstrated to be important in NASH pathogenesis, including i...

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Main Authors: Yasuhiko Nakao, Masanori Fukushima, Amy S. Mauer, Chieh-Yu Liao, Anya Ferris, Debanjali Dasgupta, Carrie Jo Heppelmann, Patrick M. Vanderboom, Mayank Saraswat, Akhilesh Pandey, K. Sreekumaran Nair, Alina M. Allen, Kazuhiko Nakao, Harmeet Malhi
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
exosome
microvesicle
DAMP
hepatocyte
StAR-related lipid transfer domain 11
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/31c87ecc88594ccfa74665a7ab1cb691
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https://doaj.org/article/31c87ecc88594ccfa74665a7ab1cb691

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