Chiral phosphoric acid catalyzed aminative dearomatization of α-naphthols/Michael addition sequence

Catalytic asymmetric dearomatization (CADA) reactions readily convert common aromatic compounds to diverse 3D chiral, polycyclic molecules. Here, the authors report an intermolecular asymmetric dearomatization of nucleophile-tethered α-naphthols affording functionalized cyclic ketones with high enan...

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Bibliographic Details
Main Authors: Zi-Lei Xia, Chao Zheng, Ren-Qi Xu, Shu-Li You
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/31cc1e810a644c278f364383ca0dac1c
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