Orchestration of protein acetylation as a toggle for cellular defense and virus replication
The dynamics of protein acetylation during infection remains unexplored. Here, Murray et al. characterize spatio-temporal acetylations of both cellular and viral proteins during HCMV infection, providing new functional insights into the host-virus acetylome that might help identify new antiviral tar...
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Nature Portfolio
2018
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oai:doaj.org-article:31cf50fe17a34c7da4208250bed5fe522021-12-02T16:49:50ZOrchestration of protein acetylation as a toggle for cellular defense and virus replication10.1038/s41467-018-07179-w2041-1723https://doaj.org/article/31cf50fe17a34c7da4208250bed5fe522018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07179-whttps://doaj.org/toc/2041-1723The dynamics of protein acetylation during infection remains unexplored. Here, Murray et al. characterize spatio-temporal acetylations of both cellular and viral proteins during HCMV infection, providing new functional insights into the host-virus acetylome that might help identify new antiviral targets.L. A. MurrayX. ShengI. M. CristeaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018) |
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Science Q L. A. Murray X. Sheng I. M. Cristea Orchestration of protein acetylation as a toggle for cellular defense and virus replication |
description |
The dynamics of protein acetylation during infection remains unexplored. Here, Murray et al. characterize spatio-temporal acetylations of both cellular and viral proteins during HCMV infection, providing new functional insights into the host-virus acetylome that might help identify new antiviral targets. |
format |
article |
author |
L. A. Murray X. Sheng I. M. Cristea |
author_facet |
L. A. Murray X. Sheng I. M. Cristea |
author_sort |
L. A. Murray |
title |
Orchestration of protein acetylation as a toggle for cellular defense and virus replication |
title_short |
Orchestration of protein acetylation as a toggle for cellular defense and virus replication |
title_full |
Orchestration of protein acetylation as a toggle for cellular defense and virus replication |
title_fullStr |
Orchestration of protein acetylation as a toggle for cellular defense and virus replication |
title_full_unstemmed |
Orchestration of protein acetylation as a toggle for cellular defense and virus replication |
title_sort |
orchestration of protein acetylation as a toggle for cellular defense and virus replication |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/31cf50fe17a34c7da4208250bed5fe52 |
work_keys_str_mv |
AT lamurray orchestrationofproteinacetylationasatoggleforcellulardefenseandvirusreplication AT xsheng orchestrationofproteinacetylationasatoggleforcellulardefenseandvirusreplication AT imcristea orchestrationofproteinacetylationasatoggleforcellulardefenseandvirusreplication |
_version_ |
1718383206536839168 |