Orchestration of protein acetylation as a toggle for cellular defense and virus replication

The dynamics of protein acetylation during infection remains unexplored. Here, Murray et al. characterize spatio-temporal acetylations of both cellular and viral proteins during HCMV infection, providing new functional insights into the host-virus acetylome that might help identify new antiviral tar...

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Autores principales: L. A. Murray, X. Sheng, I. M. Cristea
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/31cf50fe17a34c7da4208250bed5fe52
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spelling oai:doaj.org-article:31cf50fe17a34c7da4208250bed5fe522021-12-02T16:49:50ZOrchestration of protein acetylation as a toggle for cellular defense and virus replication10.1038/s41467-018-07179-w2041-1723https://doaj.org/article/31cf50fe17a34c7da4208250bed5fe522018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07179-whttps://doaj.org/toc/2041-1723The dynamics of protein acetylation during infection remains unexplored. Here, Murray et al. characterize spatio-temporal acetylations of both cellular and viral proteins during HCMV infection, providing new functional insights into the host-virus acetylome that might help identify new antiviral targets.L. A. MurrayX. ShengI. M. CristeaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
L. A. Murray
X. Sheng
I. M. Cristea
Orchestration of protein acetylation as a toggle for cellular defense and virus replication
description The dynamics of protein acetylation during infection remains unexplored. Here, Murray et al. characterize spatio-temporal acetylations of both cellular and viral proteins during HCMV infection, providing new functional insights into the host-virus acetylome that might help identify new antiviral targets.
format article
author L. A. Murray
X. Sheng
I. M. Cristea
author_facet L. A. Murray
X. Sheng
I. M. Cristea
author_sort L. A. Murray
title Orchestration of protein acetylation as a toggle for cellular defense and virus replication
title_short Orchestration of protein acetylation as a toggle for cellular defense and virus replication
title_full Orchestration of protein acetylation as a toggle for cellular defense and virus replication
title_fullStr Orchestration of protein acetylation as a toggle for cellular defense and virus replication
title_full_unstemmed Orchestration of protein acetylation as a toggle for cellular defense and virus replication
title_sort orchestration of protein acetylation as a toggle for cellular defense and virus replication
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/31cf50fe17a34c7da4208250bed5fe52
work_keys_str_mv AT lamurray orchestrationofproteinacetylationasatoggleforcellulardefenseandvirusreplication
AT xsheng orchestrationofproteinacetylationasatoggleforcellulardefenseandvirusreplication
AT imcristea orchestrationofproteinacetylationasatoggleforcellulardefenseandvirusreplication
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