Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques

SARS-CoV-2 vaccines are needed to fight the pandemic. Here, authors show protective efficacy and immunogenicity of the inactivated SARS-CoV-2 vaccine BBV152 in rhesus macaques. This vaccine is currently in clinical development.

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Autores principales: Pragya D. Yadav, Raches Ella, Sanjay Kumar, Dilip R. Patil, Sreelekshmy Mohandas, Anita M. Shete, Krishna M. Vadrevu, Gaurav Bhati, Gajanan Sapkal, Himanshu Kaushal, Savita Patil, Rajlaxmi Jain, Gururaj Deshpande, Nivedita Gupta, Kshitij Agarwal, Mangesh Gokhale, Basavaraj Mathapati, Siddhanath Metkari, Chandrashekhar Mote, Dimpal Nyayanit, Deepak Y. Patil, B. S. Sai Prasad, Annasaheb Suryawanshi, Manoj Kadam, Abhimanyu Kumar, Sachin Daigude, Sanjay Gopale, Triparna Majumdar, Deepak Mali, Prasad Sarkale, Shreekant Baradkar, Pranita Gawande, Yash Joshi, Sidharam Fulari, Hitesh Dighe, Sharda Sharma, Rashmi Gunjikar, Abhinendra Kumar, Kaumudi Kalele, Vellimedu K. Srinivas, Raman R. Gangakhedkar, Krishna M. Ella, Priya Abraham, Samiran Panda, Balram Bhargava
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/31d3828a5c414597afab7a582efa0951
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spelling oai:doaj.org-article:31d3828a5c414597afab7a582efa09512021-12-02T13:35:00ZImmunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques10.1038/s41467-021-21639-w2041-1723https://doaj.org/article/31d3828a5c414597afab7a582efa09512021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21639-whttps://doaj.org/toc/2041-1723SARS-CoV-2 vaccines are needed to fight the pandemic. Here, authors show protective efficacy and immunogenicity of the inactivated SARS-CoV-2 vaccine BBV152 in rhesus macaques. This vaccine is currently in clinical development.Pragya D. YadavRaches EllaSanjay KumarDilip R. PatilSreelekshmy MohandasAnita M. SheteKrishna M. VadrevuGaurav BhatiGajanan SapkalHimanshu KaushalSavita PatilRajlaxmi JainGururaj DeshpandeNivedita GuptaKshitij AgarwalMangesh GokhaleBasavaraj MathapatiSiddhanath MetkariChandrashekhar MoteDimpal NyayanitDeepak Y. PatilB. S. Sai PrasadAnnasaheb SuryawanshiManoj KadamAbhimanyu KumarSachin DaigudeSanjay GopaleTriparna MajumdarDeepak MaliPrasad SarkaleShreekant BaradkarPranita GawandeYash JoshiSidharam FulariHitesh DigheSharda SharmaRashmi GunjikarAbhinendra KumarKaumudi KaleleVellimedu K. SrinivasRaman R. GangakhedkarKrishna M. EllaPriya AbrahamSamiran PandaBalram BhargavaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Pragya D. Yadav
Raches Ella
Sanjay Kumar
Dilip R. Patil
Sreelekshmy Mohandas
Anita M. Shete
Krishna M. Vadrevu
Gaurav Bhati
Gajanan Sapkal
Himanshu Kaushal
Savita Patil
Rajlaxmi Jain
Gururaj Deshpande
Nivedita Gupta
Kshitij Agarwal
Mangesh Gokhale
Basavaraj Mathapati
Siddhanath Metkari
Chandrashekhar Mote
Dimpal Nyayanit
Deepak Y. Patil
B. S. Sai Prasad
Annasaheb Suryawanshi
Manoj Kadam
Abhimanyu Kumar
Sachin Daigude
Sanjay Gopale
Triparna Majumdar
Deepak Mali
Prasad Sarkale
Shreekant Baradkar
Pranita Gawande
Yash Joshi
Sidharam Fulari
Hitesh Dighe
Sharda Sharma
Rashmi Gunjikar
Abhinendra Kumar
Kaumudi Kalele
Vellimedu K. Srinivas
Raman R. Gangakhedkar
Krishna M. Ella
Priya Abraham
Samiran Panda
Balram Bhargava
Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques
description SARS-CoV-2 vaccines are needed to fight the pandemic. Here, authors show protective efficacy and immunogenicity of the inactivated SARS-CoV-2 vaccine BBV152 in rhesus macaques. This vaccine is currently in clinical development.
format article
author Pragya D. Yadav
Raches Ella
Sanjay Kumar
Dilip R. Patil
Sreelekshmy Mohandas
Anita M. Shete
Krishna M. Vadrevu
Gaurav Bhati
Gajanan Sapkal
Himanshu Kaushal
Savita Patil
Rajlaxmi Jain
Gururaj Deshpande
Nivedita Gupta
Kshitij Agarwal
Mangesh Gokhale
Basavaraj Mathapati
Siddhanath Metkari
Chandrashekhar Mote
Dimpal Nyayanit
Deepak Y. Patil
B. S. Sai Prasad
Annasaheb Suryawanshi
Manoj Kadam
Abhimanyu Kumar
Sachin Daigude
Sanjay Gopale
Triparna Majumdar
Deepak Mali
Prasad Sarkale
Shreekant Baradkar
Pranita Gawande
Yash Joshi
Sidharam Fulari
Hitesh Dighe
Sharda Sharma
Rashmi Gunjikar
Abhinendra Kumar
Kaumudi Kalele
Vellimedu K. Srinivas
Raman R. Gangakhedkar
Krishna M. Ella
Priya Abraham
Samiran Panda
Balram Bhargava
author_facet Pragya D. Yadav
Raches Ella
Sanjay Kumar
Dilip R. Patil
Sreelekshmy Mohandas
Anita M. Shete
Krishna M. Vadrevu
Gaurav Bhati
Gajanan Sapkal
Himanshu Kaushal
Savita Patil
Rajlaxmi Jain
Gururaj Deshpande
Nivedita Gupta
Kshitij Agarwal
Mangesh Gokhale
Basavaraj Mathapati
Siddhanath Metkari
Chandrashekhar Mote
Dimpal Nyayanit
Deepak Y. Patil
B. S. Sai Prasad
Annasaheb Suryawanshi
Manoj Kadam
Abhimanyu Kumar
Sachin Daigude
Sanjay Gopale
Triparna Majumdar
Deepak Mali
Prasad Sarkale
Shreekant Baradkar
Pranita Gawande
Yash Joshi
Sidharam Fulari
Hitesh Dighe
Sharda Sharma
Rashmi Gunjikar
Abhinendra Kumar
Kaumudi Kalele
Vellimedu K. Srinivas
Raman R. Gangakhedkar
Krishna M. Ella
Priya Abraham
Samiran Panda
Balram Bhargava
author_sort Pragya D. Yadav
title Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques
title_short Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques
title_full Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques
title_fullStr Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques
title_full_unstemmed Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques
title_sort immunogenicity and protective efficacy of inactivated sars-cov-2 vaccine candidate, bbv152 in rhesus macaques
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/31d3828a5c414597afab7a582efa0951
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