Vial coring and fragmentation incidence after angled penetration of rubber stoppers with single-use hypodermic needles

Particles due to fragmentation present a clear risk to the patient. Reported fragmentation rates vary, and an insertion angle at 45°, as opposed to 90°, has been proposed as a mitigation strategy. So, this study evaluated the fragmentation rates induced by single-use hypodermic needles using differe...

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Autores principales:	Rase Marissa, Hanlon Mark, Ho Le, Duriez Doug, Zhao Cathy
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	container closure systems coring fragmentation parenteral drug products patient safety rubber stoppers Therapeutics. Pharmacology RM1-950 Pharmaceutical industry HD9665-9675
Acceso en línea:	https://doaj.org/article/31d40b0d1ad344019189fa7f5894cb0e
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spelling	oai:doaj.org-article:31d40b0d1ad344019189fa7f5894cb0e2021-12-05T14:11:02ZVial coring and fragmentation incidence after angled penetration of rubber stoppers with single-use hypodermic needles2365-24112365-242X10.1515/pthp-2021-0004https://doaj.org/article/31d40b0d1ad344019189fa7f5894cb0e2021-09-01T00:00:00Zhttps://doi.org/10.1515/pthp-2021-0004https://doaj.org/toc/2365-2411https://doaj.org/toc/2365-242XParticles due to fragmentation present a clear risk to the patient. Reported fragmentation rates vary, and an insertion angle at 45°, as opposed to 90°, has been proposed as a mitigation strategy. So, this study evaluated the fragmentation rates induced by single-use hypodermic needles using different angled penetration techniques.Rase MarissaHanlon MarkHo LeDuriez DougZhao CathyDe Gruyterarticlecontainer closure systemscoringfragmentationparenteral drug productspatient safetyrubber stoppersTherapeutics. PharmacologyRM1-950Pharmaceutical industryHD9665-9675ENPharmaceutical Technology in Hospital Pharmacy, Vol 6, Iss 1, Pp 165-74 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	container closure systems coring fragmentation parenteral drug products patient safety rubber stoppers Therapeutics. Pharmacology RM1-950 Pharmaceutical industry HD9665-9675
spellingShingle	container closure systems coring fragmentation parenteral drug products patient safety rubber stoppers Therapeutics. Pharmacology RM1-950 Pharmaceutical industry HD9665-9675 Rase Marissa Hanlon Mark Ho Le Duriez Doug Zhao Cathy Vial coring and fragmentation incidence after angled penetration of rubber stoppers with single-use hypodermic needles
description	Particles due to fragmentation present a clear risk to the patient. Reported fragmentation rates vary, and an insertion angle at 45°, as opposed to 90°, has been proposed as a mitigation strategy. So, this study evaluated the fragmentation rates induced by single-use hypodermic needles using different angled penetration techniques.
format	article
author	Rase Marissa Hanlon Mark Ho Le Duriez Doug Zhao Cathy
author_facet	Rase Marissa Hanlon Mark Ho Le Duriez Doug Zhao Cathy
author_sort	Rase Marissa
title	Vial coring and fragmentation incidence after angled penetration of rubber stoppers with single-use hypodermic needles
title_short	Vial coring and fragmentation incidence after angled penetration of rubber stoppers with single-use hypodermic needles
title_full	Vial coring and fragmentation incidence after angled penetration of rubber stoppers with single-use hypodermic needles
title_fullStr	Vial coring and fragmentation incidence after angled penetration of rubber stoppers with single-use hypodermic needles
title_full_unstemmed	Vial coring and fragmentation incidence after angled penetration of rubber stoppers with single-use hypodermic needles
title_sort	vial coring and fragmentation incidence after angled penetration of rubber stoppers with single-use hypodermic needles
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/31d40b0d1ad344019189fa7f5894cb0e
work_keys_str_mv	AT rasemarissa vialcoringandfragmentationincidenceafterangledpenetrationofrubberstopperswithsingleusehypodermicneedles AT hanlonmark vialcoringandfragmentationincidenceafterangledpenetrationofrubberstopperswithsingleusehypodermicneedles AT hole vialcoringandfragmentationincidenceafterangledpenetrationofrubberstopperswithsingleusehypodermicneedles AT duriezdoug vialcoringandfragmentationincidenceafterangledpenetrationofrubberstopperswithsingleusehypodermicneedles AT zhaocathy vialcoringandfragmentationincidenceafterangledpenetrationofrubberstopperswithsingleusehypodermicneedles
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Vial coring and fragmentation incidence after angled penetration of rubber stoppers with single-use hypodermic needles

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