SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum

Endoplasmic reticulum (ER)-interorganelle membrane contact sites have emerged as key regulators of organelle dynamics. Here, the authors report that the ER-resident protein SNX19 mediates ER-endolysosome membrane contacts to maintain the perinuclear distribution of endolysosomes and restrict their m...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Amra Saric, Spencer A. Freeman, Chad D. Williamson, Michal Jarnik, Carlos M. Guardia, Michael S. Fernandopulle, David C. Gershlick, Juan S. Bonifacino
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/31d67507b07347d8ba1e4e2dbd2246c1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:31d67507b07347d8ba1e4e2dbd2246c1
record_format	dspace
spelling	oai:doaj.org-article:31d67507b07347d8ba1e4e2dbd2246c12021-12-02T18:46:58ZSNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum10.1038/s41467-021-24709-12041-1723https://doaj.org/article/31d67507b07347d8ba1e4e2dbd2246c12021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24709-1https://doaj.org/toc/2041-1723Endoplasmic reticulum (ER)-interorganelle membrane contact sites have emerged as key regulators of organelle dynamics. Here, the authors report that the ER-resident protein SNX19 mediates ER-endolysosome membrane contacts to maintain the perinuclear distribution of endolysosomes and restrict their motility.Amra SaricSpencer A. FreemanChad D. WilliamsonMichal JarnikCarlos M. GuardiaMichael S. FernandopulleDavid C. GershlickJuan S. BonifacinoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Amra Saric Spencer A. Freeman Chad D. Williamson Michal Jarnik Carlos M. Guardia Michael S. Fernandopulle David C. Gershlick Juan S. Bonifacino SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum
description	Endoplasmic reticulum (ER)-interorganelle membrane contact sites have emerged as key regulators of organelle dynamics. Here, the authors report that the ER-resident protein SNX19 mediates ER-endolysosome membrane contacts to maintain the perinuclear distribution of endolysosomes and restrict their motility.
format	article
author	Amra Saric Spencer A. Freeman Chad D. Williamson Michal Jarnik Carlos M. Guardia Michael S. Fernandopulle David C. Gershlick Juan S. Bonifacino
author_facet	Amra Saric Spencer A. Freeman Chad D. Williamson Michal Jarnik Carlos M. Guardia Michael S. Fernandopulle David C. Gershlick Juan S. Bonifacino
author_sort	Amra Saric
title	SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum
title_short	SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum
title_full	SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum
title_fullStr	SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum
title_full_unstemmed	SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum
title_sort	snx19 restricts endolysosome motility through contacts with the endoplasmic reticulum
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/31d67507b07347d8ba1e4e2dbd2246c1
work_keys_str_mv	AT amrasaric snx19restrictsendolysosomemotilitythroughcontactswiththeendoplasmicreticulum AT spencerafreeman snx19restrictsendolysosomemotilitythroughcontactswiththeendoplasmicreticulum AT chaddwilliamson snx19restrictsendolysosomemotilitythroughcontactswiththeendoplasmicreticulum AT michaljarnik snx19restrictsendolysosomemotilitythroughcontactswiththeendoplasmicreticulum AT carlosmguardia snx19restrictsendolysosomemotilitythroughcontactswiththeendoplasmicreticulum AT michaelsfernandopulle snx19restrictsendolysosomemotilitythroughcontactswiththeendoplasmicreticulum AT davidcgershlick snx19restrictsendolysosomemotilitythroughcontactswiththeendoplasmicreticulum AT juansbonifacino snx19restrictsendolysosomemotilitythroughcontactswiththeendoplasmicreticulum
_version_	1718377671890567168

SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum

Ejemplares similares