Cell Cycle Inhibition To Treat Sleeping Sickness

Código QR

Cell Cycle Inhibition To Treat Sleeping Sickness

ABSTRACT African trypanosomiasis is caused by infection with the protozoan parasite Trypanosoma brucei. During infection, this pathogen divides rapidly to high density in the bloodstream of its mammalian host in a manner similar to that of leukemia. Like all eukaryotes, T. brucei has a cell cycle in...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Conrad L. Epting, Brian T. Emmer, Nga Y. Du, Joann M. Taylor, Ming Y. Makanji, Cheryl L. Olson, David M. Engman
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2017
Materias:	African sleeping sickness Trypanosoma brucei hydroxyurea ribonucleotide reductase Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/31d7a561c496421a96c0f83003ea87a1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Manipulating the Bacterial Cell Cycle and Cell Size by Titrating the Expression of Ribonucleotide Reductase
por: Manlu Zhu, et al.
Publicado: (2017)

The Mitochondrial Ca<sup>2+</sup> Uniporter Complex (MCUC) of <named-content content-type="genus-species">Trypanosoma brucei</named-content> Is a Hetero-oligomer That Contains Novel Subunits Essential for Ca<sup>2+</sup> Uptake
por: Guozhong Huang, et al.
Publicado: (2018)

Observations on Estrus as Monitored by Receptivity to Mating Activity and Pattern of Vaginal Exfoliates In Trypanosoma brucei Infected WAD Goat does Synchronized with Estrumate®
por: Leigh,Olufisayo Oluwadamilare, et al.
Publicado: (2011)

Rapid, Selection-Free, High-Efficiency Genome Editing in Protozoan Parasites Using CRISPR-Cas9 Ribonucleoproteins
por: Lia Carolina Soares Medeiros, et al.
Publicado: (2017)

Functional Analyses of Cytokinesis Regulators in Bloodstream Stage <named-content content-type="genus-species">Trypanosoma brucei</named-content> Parasites Identify Functions and Regulations Specific to the Life Cycle Stage
por: Xuan Zhang, et al.
Publicado: (2019)

Structural Characterization of Acidic M17 Leucine Aminopeptidases from the TriTryps and Evaluation of Their Role in Nutrient Starvation in <named-content content-type="genus-species">Trypanosoma brucei</named-content>
por: Jennifer Timm, et al.
Publicado: (2017)

RNase III Domain of KREPB9 and KREPB10 Association with Editosomes in <named-content content-type="genus-species">Trypanosoma brucei</named-content>
por: Jason Carnes, et al.
Publicado: (2018)

<named-content content-type="genus-species">Trypanosoma brucei</named-content> Pex13.2 Is an Accessory Peroxin That Functions in the Import of Peroxisome Targeting Sequence Type 2 Proteins and Localizes to Subdomains of the Glycosome
por: Logan P. Crowe, et al.
Publicado: (2020)

Contribution of Cytidine Deaminase to Thymidylate Biosynthesis in <named-content content-type="genus-species">Trypanosoma brucei</named-content>: Intracellular Localization and Properties of the Enzyme
por: Ana Moro-Bulnes, et al.
Publicado: (2019)

The Cross Talk between TbTim50 and PIP39, Two Aspartate-Based Protein Phosphatases, Maintains Cellular Homeostasis in <named-content content-type="genus-species">Trypanosoma brucei</named-content>
por: Anuj Tripathi, et al.
Publicado: (2019)

<named-content content-type="genus-species">Trypanosoma brucei</named-content> RAP1 Has Essential Functional Domains That Are Required for Different Protein Interactions
por: Marjia Afrin, et al.
Publicado: (2020)

Divergent Small Tim Homologues Are Associated with TbTim17 and Critical for the Biogenesis of TbTim17 Protein Complexes in <italic toggle="yes">Trypanosoma brucei</italic>
por: Joseph T. Smith, et al.
Publicado: (2018)

Age as a risk factor for acute mountain sickness upon rapid ascent to 3,700 m among young adult Chinese men
por: Tang XG, et al.
Publicado: (2014)

Regulation of <italic toggle="yes">Trypanosoma brucei</italic> Acetyl Coenzyme A Carboxylase by Environmental Lipids
por: Sunayan S. Ray, et al.
Publicado: (2018)

Basal Body Protein TbSAF1 Is Required for Microtubule Quartet Anchorage to the Basal Bodies in <italic toggle="yes">Trypanosoma brucei</italic>
por: Xiaoduo Dong, et al.
Publicado: (2020)

<named-content content-type="genus-species">Trypanosoma brucei</named-content> PRMT1 Is a Nucleic Acid Binding Protein with a Role in Energy Metabolism and the Starvation Stress Response
por: Lucie Kafková, et al.
Publicado: (2018)

Expression patterns and prognostic significances of RRM1 and ERCC1 in pancreatic carcinoma and cholangiocarcinoma
por: Khushbu Khetan, et al.
Publicado: (2021)

Novel Cytoskeleton-Associated Proteins in <i>Trypanosoma brucei</i> Are Essential for Cell Morphogenesis and Cytokinesis
por: Marina Schock, et al.
Publicado: (2021)

Pyrophosphate Stimulates the Phosphate-Sodium Symporter of <italic toggle="yes">Trypanosoma brucei</italic> Acidocalcisomes and <italic toggle="yes">Saccharomyces cerevisiae</italic> Vacuoles
por: Evgeniy Potapenko, et al.
Publicado: (2019)

mSphere of Influence: Expanding the CRISPR Sphere with Single-Locus Proteomics
por: Lucy Glover
Publicado: (2020)

Serum sickness-like reaction following an administration of the first dose of inactivated COVID19 vaccine
por: Sasipim Chaijaras, MD, et al.
Publicado: (2022)

Antitrypanosomal Activity of <i>Anthriscus</i> Nemorosa Essential Oils and Combinations of Their Main Constituents
por: Cecilia Baldassarri, et al.
Publicado: (2021)

Differential adaptability between reference strains and clinical isolates of Pseudomonas aeruginosa into the lung epithelium intracellular lifestyle
por: Maria Del Mar Cendra, et al.
Publicado: (2020)

Occupation and Sickness Absence in the Different Autonomous Communities of Spain
por: Matilde Leonor Alba-Jurado, et al.
Publicado: (2021)

Immunological Mechanisms of Sickness Behavior in Viral Infection
por: Mia Krapić, et al.
Publicado: (2021)

Neurocognitive domains and neuropathological changes in experimental infection with Trypanosoma brucei brucei in Wistar rats
por: Olamide Elizabeth Adebiyi, et al.
Publicado: (2021)

The impact of biologically active additives on the indices of immune status of sickly children
por: E. N. Tsybikova, et al.
Publicado: (2013)

THE ANALYSIS OF THE SICKNESS RATE AMONG THE CHILDREN AND ADOLESCENTS OF THE IRKUTSK REGION (BY EXAMPLE OF THE TAISHET DISTRICT)
por: I. V. Donskikh
Publicado: (2013)

Arguing in Favor of Revising the Simulator Sickness Questionnaire Factor Structure When Assessing Side Effects Induced by Immersions in Virtual Reality
por: Stéphane Bouchard, et al.
Publicado: (2021)

Clinical and allergological analysis of ocular manifestations of sick building syndrome
por: Saeki Y, et al.
Publicado: (2017)

THEORETICAL MODEL OF ALDOLASE FRUCTOSE 1,6 BIPHOSPHATE FROM Trypanosome brucei
por: CORDERO DE TROCONIS,MARYI, et al.
Publicado: (2010)

Causes of Sickness Absenteeism in Europe—Analysis from an Intercountry and Gender Perspective
por: Elżbieta Antczak, et al.
Publicado: (2021)

Sharing an environment with sick conspecifics alters odors of healthy animals
por: Stephanie S. Gervasi, et al.
Publicado: (2018)

Demographic, Lifestyle, and Physical Health Predictors of Sickness Absenteeism in Nursing: A Meta-Analysis
por: Basem Gohar, et al.
Publicado: (2021)

Sick leave characteristics among nurses of a referral hospital during COVID-19 epidemic
por: Arezoo Najafi, et al.
Publicado: (2021)

Vestibular Morphological Asymmetry Associated With Motion Sickness Susceptibility
por: Takumi Harada, et al.
Publicado: (2021)

Hydroxyurea Induces Bone Marrow Mesenchymal Stromal Cells Senescence and Modifies Cell Functionality In Vitro
por: Sunčica Kapor, et al.
Publicado: (2021)

Incidence and severity of Visually Induced motion Sickness during 3D laparoscopy In Operators who had No experience with it (VISION)
por: Young Han, et al.
Publicado: (2020)

Serum Sickness-Like Reaction: Drug-Induced Cutaneous Disease in a Child
por: Ana Carolina Galvão dos Santos de Araujo, et al.
Publicado: (2021)

The role of managerial leadership in sickness absence in health and social care: antecedent or moderator in the association between psychosocial working conditions and register-based sickness absence? A longitudinal study based on a swedish cohort
por: Johanna Stengård, et al.
Publicado: (2021)