Phenotypic T cell exhaustion in a murine model of bacterial infection in the setting of pre-existing malignancy.

While much of cancer immunology research has focused on anti-tumor immunity both systemically and within the tumor microenvironment, little is known about the impact of pre-existing malignancy on pathogen-specific immune responses. Here, we sought to characterize the antigen-specific CD8+ T cell res...

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Autores principales: Rohit Mittal, Maylene Wagener, Elise R Breed, Zhe Liang, Benyam P Yoseph, Eileen M Burd, Alton B Farris, Craig M Coopersmith, Mandy L Ford
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/31e83b4735fe437e86aaef097708f8e5
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