RNA structure drives interaction with proteins

Interactions between protein and RNA occur on a large scale, and are often studied from a proteincentric point of view. Here the authors show that the number and strength of RNA-protein interactions correlate with the amount of RNA structure, which impacts the biological activity of the transcript.

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Detalles Bibliográficos
Autores principales: Natalia Sanchez de Groot, Alexandros Armaos, Ricardo Graña-Montes, Marion Alriquet, Giulia Calloni, R. Martin Vabulas, Gian Gaetano Tartaglia
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/31f388900b7443e7841250a2030095c4
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Descripción
Sumario:Interactions between protein and RNA occur on a large scale, and are often studied from a proteincentric point of view. Here the authors show that the number and strength of RNA-protein interactions correlate with the amount of RNA structure, which impacts the biological activity of the transcript.