RNA structure drives interaction with proteins

Interactions between protein and RNA occur on a large scale, and are often studied from a proteincentric point of view. Here the authors show that the number and strength of RNA-protein interactions correlate with the amount of RNA structure, which impacts the biological activity of the transcript.

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Autores principales: Natalia Sanchez de Groot, Alexandros Armaos, Ricardo Graña-Montes, Marion Alriquet, Giulia Calloni, R. Martin Vabulas, Gian Gaetano Tartaglia
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/31f388900b7443e7841250a2030095c4
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spelling oai:doaj.org-article:31f388900b7443e7841250a2030095c42021-12-02T14:39:20ZRNA structure drives interaction with proteins10.1038/s41467-019-10923-52041-1723https://doaj.org/article/31f388900b7443e7841250a2030095c42019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10923-5https://doaj.org/toc/2041-1723Interactions between protein and RNA occur on a large scale, and are often studied from a proteincentric point of view. Here the authors show that the number and strength of RNA-protein interactions correlate with the amount of RNA structure, which impacts the biological activity of the transcript.Natalia Sanchez de GrootAlexandros ArmaosRicardo Graña-MontesMarion AlriquetGiulia CalloniR. Martin VabulasGian Gaetano TartagliaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Natalia Sanchez de Groot
Alexandros Armaos
Ricardo Graña-Montes
Marion Alriquet
Giulia Calloni
R. Martin Vabulas
Gian Gaetano Tartaglia
RNA structure drives interaction with proteins
description Interactions between protein and RNA occur on a large scale, and are often studied from a proteincentric point of view. Here the authors show that the number and strength of RNA-protein interactions correlate with the amount of RNA structure, which impacts the biological activity of the transcript.
format article
author Natalia Sanchez de Groot
Alexandros Armaos
Ricardo Graña-Montes
Marion Alriquet
Giulia Calloni
R. Martin Vabulas
Gian Gaetano Tartaglia
author_facet Natalia Sanchez de Groot
Alexandros Armaos
Ricardo Graña-Montes
Marion Alriquet
Giulia Calloni
R. Martin Vabulas
Gian Gaetano Tartaglia
author_sort Natalia Sanchez de Groot
title RNA structure drives interaction with proteins
title_short RNA structure drives interaction with proteins
title_full RNA structure drives interaction with proteins
title_fullStr RNA structure drives interaction with proteins
title_full_unstemmed RNA structure drives interaction with proteins
title_sort rna structure drives interaction with proteins
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/31f388900b7443e7841250a2030095c4
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AT marionalriquet rnastructuredrivesinteractionwithproteins
AT giuliacalloni rnastructuredrivesinteractionwithproteins
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