Nutrition, Obesity and Asthma Inception in Children. The Role of Lung Function

Obesity is an important public health problem. WHO estimates that about 39 million children younger than 5 years of age are overweighted or obese. On the other hand, asthma is the most prevalent chronic disease in childhood, and thus, many children share those two conditions. In the present paper we...

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Autores principales:	Sanchez-Solís Manuel, García-Marcos Luis
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	asthma obesity epidemiology dysanapsis childhood Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/31f59b9f16af47349d46eb0897dccb97
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id	oai:doaj.org-article:31f59b9f16af47349d46eb0897dccb97
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spelling	oai:doaj.org-article:31f59b9f16af47349d46eb0897dccb972021-11-25T18:34:32ZNutrition, Obesity and Asthma Inception in Children. The Role of Lung Function10.3390/nu131138372072-6643https://doaj.org/article/31f59b9f16af47349d46eb0897dccb972021-10-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/3837https://doaj.org/toc/2072-6643Obesity is an important public health problem. WHO estimates that about 39 million children younger than 5 years of age are overweighted or obese. On the other hand, asthma is the most prevalent chronic disease in childhood, and thus, many children share those two conditions. In the present paper we review the epidemiology of children with asthma and obesity, as well as the consequences of being obese on the respiratory system. On the one hand obesity produces an underlying T-helper 2 (TH2) low inflammation state in which numerous cytokines, which could have an impact in the respiratory system play, a role. On the other hand, some respiratory changes have been described in obese children and, specially, the development of the so called “dysanapsis” (the disproportionate scaling of airway dimensions to lung volume) which seems to be common during the first stages of life, probably related to the early development of this condition. Finally, this review deals with the role of adipokines and insulin resistance in the inception and worsening of asthma in the obese child.Sanchez-Solís ManuelGarcía-Marcos LuisMDPI AGarticleasthmaobesityepidemiologydysanapsischildhoodNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 3837, p 3837 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	asthma obesity epidemiology dysanapsis childhood Nutrition. Foods and food supply TX341-641
spellingShingle	asthma obesity epidemiology dysanapsis childhood Nutrition. Foods and food supply TX341-641 Sanchez-Solís Manuel García-Marcos Luis Nutrition, Obesity and Asthma Inception in Children. The Role of Lung Function
description	Obesity is an important public health problem. WHO estimates that about 39 million children younger than 5 years of age are overweighted or obese. On the other hand, asthma is the most prevalent chronic disease in childhood, and thus, many children share those two conditions. In the present paper we review the epidemiology of children with asthma and obesity, as well as the consequences of being obese on the respiratory system. On the one hand obesity produces an underlying T-helper 2 (TH2) low inflammation state in which numerous cytokines, which could have an impact in the respiratory system play, a role. On the other hand, some respiratory changes have been described in obese children and, specially, the development of the so called “dysanapsis” (the disproportionate scaling of airway dimensions to lung volume) which seems to be common during the first stages of life, probably related to the early development of this condition. Finally, this review deals with the role of adipokines and insulin resistance in the inception and worsening of asthma in the obese child.
format	article
author	Sanchez-Solís Manuel García-Marcos Luis
author_facet	Sanchez-Solís Manuel García-Marcos Luis
author_sort	Sanchez-Solís Manuel
title	Nutrition, Obesity and Asthma Inception in Children. The Role of Lung Function
title_short	Nutrition, Obesity and Asthma Inception in Children. The Role of Lung Function
title_full	Nutrition, Obesity and Asthma Inception in Children. The Role of Lung Function
title_fullStr	Nutrition, Obesity and Asthma Inception in Children. The Role of Lung Function
title_full_unstemmed	Nutrition, Obesity and Asthma Inception in Children. The Role of Lung Function
title_sort	nutrition, obesity and asthma inception in children. the role of lung function
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/31f59b9f16af47349d46eb0897dccb97
work_keys_str_mv	AT sanchezsolismanuel nutritionobesityandasthmainceptioninchildrentheroleoflungfunction AT garciamarcosluis nutritionobesityandasthmainceptioninchildrentheroleoflungfunction
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Nutrition, Obesity and Asthma Inception in Children. The Role of Lung Function

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