Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions

The CORVET complex is a multi-subunit complex that regulates fusion between early endosomes. Here the authors show that the CORVET subunits Vps3 and Vps8 also regulate vesicular transport from early to recycling endosomes and are required for recycling integrins to the plasma membrane.

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Autores principales:	C. T. H. Jonker, R. Galmes, T. Veenendaal, C. ten Brink, R. E. N. van der Welle, N. Liv, J. de Rooij, A. A. Peden, P. van der Sluijs, C. Margadant, J. Klumperman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/31fce15579cd4618bf9885b76d085d77
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spelling	oai:doaj.org-article:31fce15579cd4618bf9885b76d085d772021-12-02T16:49:19ZVps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions10.1038/s41467-018-03226-82041-1723https://doaj.org/article/31fce15579cd4618bf9885b76d085d772018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03226-8https://doaj.org/toc/2041-1723The CORVET complex is a multi-subunit complex that regulates fusion between early endosomes. Here the authors show that the CORVET subunits Vps3 and Vps8 also regulate vesicular transport from early to recycling endosomes and are required for recycling integrins to the plasma membrane.C. T. H. JonkerR. GalmesT. VeenendaalC. ten BrinkR. E. N. van der WelleN. LivJ. de RooijA. A. PedenP. van der SluijsC. MargadantJ. KlumpermanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q C. T. H. Jonker R. Galmes T. Veenendaal C. ten Brink R. E. N. van der Welle N. Liv J. de Rooij A. A. Peden P. van der Sluijs C. Margadant J. Klumperman Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions
description	The CORVET complex is a multi-subunit complex that regulates fusion between early endosomes. Here the authors show that the CORVET subunits Vps3 and Vps8 also regulate vesicular transport from early to recycling endosomes and are required for recycling integrins to the plasma membrane.
format	article
author	C. T. H. Jonker R. Galmes T. Veenendaal C. ten Brink R. E. N. van der Welle N. Liv J. de Rooij A. A. Peden P. van der Sluijs C. Margadant J. Klumperman
author_facet	C. T. H. Jonker R. Galmes T. Veenendaal C. ten Brink R. E. N. van der Welle N. Liv J. de Rooij A. A. Peden P. van der Sluijs C. Margadant J. Klumperman
author_sort	C. T. H. Jonker
title	Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions
title_short	Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions
title_full	Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions
title_fullStr	Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions
title_full_unstemmed	Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions
title_sort	vps3 and vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/31fce15579cd4618bf9885b76d085d77
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Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions

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