Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions

Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions

The CORVET complex is a multi-subunit complex that regulates fusion between early endosomes. Here the authors show that the CORVET subunits Vps3 and Vps8 also regulate vesicular transport from early to recycling endosomes and are required for recycling integrins to the plasma membrane.

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Detalles Bibliográficos
Autores principales: C. T. H. Jonker, R. Galmes, T. Veenendaal, C. ten Brink, R. E. N. van der Welle, N. Liv, J. de Rooij, A. A. Peden, P. van der Sluijs, C. Margadant, J. Klumperman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
Q
Acceso en línea:https://doaj.org/article/31fce15579cd4618bf9885b76d085d77
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