Treatment of macular edema due to retinal vein occlusions

Roomasa Channa, Michael Smith, Peter A CampochiaroDepartments of Ophthalmology and Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD, USA Abstract: Retinal vein occlusion (RVO) is a prevalent retinal vascular disease, second only to diabetic retinopathy. Previously there w...

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Autores principales:	Channa R, Smith M, Campochiaro P
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/320278310e2944ee85090841034f2dbf
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spelling	oai:doaj.org-article:320278310e2944ee85090841034f2dbf2021-12-02T06:37:21ZTreatment of macular edema due to retinal vein occlusions1177-54671177-5483https://doaj.org/article/320278310e2944ee85090841034f2dbf2011-05-01T00:00:00Zhttp://www.dovepress.com/treatment-of-macular-edema-due-to-retinal-vein-occlusions-a7511https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Roomasa Channa, Michael Smith, Peter A CampochiaroDepartments of Ophthalmology and Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD, USA Abstract: Retinal vein occlusion (RVO) is a prevalent retinal vascular disease, second only to diabetic retinopathy. Previously there was no treatment for central retinal vein occlusion (CRVO) and patients were simply observed for the development of severe complications, generally resulting in poor visual outcomes. The only treatment for branch vein occlusion (BRVO) was grid laser photocoagulation, which reduces edema very slowly and provides benefit in some, but not all patients. Within the past year, clinical trials have demonstrated the effects of three new pharmacologic treatments, ranibizumab, triamcinolone acetonide, and dexamethasone implants. The benefit/risk ratio is best for intraocular injections of ranibizumab, making this first-line therapy for most patients with CRVO or BRVO, while intraocular steroids are likely to play adjunctive roles. Standard care for patients with RVO has changed and will continue to evolve as results with other new agents are revealed.Keywords: vascular endothelial growth factor, triamcinolone acetonide, dexamethosone implant, sustained release, vascular leakage, ischemiaChanna RSmith MCampochiaro PDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 705-713 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Channa R Smith M Campochiaro P Treatment of macular edema due to retinal vein occlusions
description	Roomasa Channa, Michael Smith, Peter A CampochiaroDepartments of Ophthalmology and Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD, USA Abstract: Retinal vein occlusion (RVO) is a prevalent retinal vascular disease, second only to diabetic retinopathy. Previously there was no treatment for central retinal vein occlusion (CRVO) and patients were simply observed for the development of severe complications, generally resulting in poor visual outcomes. The only treatment for branch vein occlusion (BRVO) was grid laser photocoagulation, which reduces edema very slowly and provides benefit in some, but not all patients. Within the past year, clinical trials have demonstrated the effects of three new pharmacologic treatments, ranibizumab, triamcinolone acetonide, and dexamethasone implants. The benefit/risk ratio is best for intraocular injections of ranibizumab, making this first-line therapy for most patients with CRVO or BRVO, while intraocular steroids are likely to play adjunctive roles. Standard care for patients with RVO has changed and will continue to evolve as results with other new agents are revealed.Keywords: vascular endothelial growth factor, triamcinolone acetonide, dexamethosone implant, sustained release, vascular leakage, ischemia
format	article
author	Channa R Smith M Campochiaro P
author_facet	Channa R Smith M Campochiaro P
author_sort	Channa R
title	Treatment of macular edema due to retinal vein occlusions
title_short	Treatment of macular edema due to retinal vein occlusions
title_full	Treatment of macular edema due to retinal vein occlusions
title_fullStr	Treatment of macular edema due to retinal vein occlusions
title_full_unstemmed	Treatment of macular edema due to retinal vein occlusions
title_sort	treatment of macular edema due to retinal vein occlusions
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/320278310e2944ee85090841034f2dbf
work_keys_str_mv	AT channar treatmentofmacularedemaduetoretinalveinocclusions AT smithm treatmentofmacularedemaduetoretinalveinocclusions AT campochiarop treatmentofmacularedemaduetoretinalveinocclusions
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Treatment of macular edema due to retinal vein occlusions

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