Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities

Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities

Understanding the heterogeneity of peritoneal macrophages is hampered by controversy over their origin and homeostasis. Here the authors show the embryonic F4/80hi population is replaced over time by self-renewing bone marrow-derived cells transitioning from F4/80lo to F4/80hi in adult mice, and tha...

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Autores principales: Calum C. Bain, Catherine A. Hawley, Hannah Garner, Charlotte L. Scott, Anika Schridde, Nicholas J. Steers, Matthias Mack, Anagha Joshi, Martin Guilliams, Allan Mc I. Mowat, Frederic Geissmann, Stephen J. Jenkins
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/320587b30d454079837bd3319d6310c0
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