Noise-induced bistability in the fate of cancer phenotypic quasispecies: a bit-strings approach

Abstract Tumor cell populations are highly heterogeneous. Such heterogeneity, both at genotypic and phenotypic levels, is a key feature during tumorigenesis. How to investigate the impact of this heterogeneity in the dynamics of tumors cells becomes an important issue. Here we explore a stochastic m...

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Autores principales: Josep Sardanyés, Tomás Alarcón
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/3207f854678f43bcb0537911da90ed80
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