Type I Kounis syndrome variant: A case report and literature review

Kounis syndrome defined as the occurrence of acute coronary syndrome in the setting of allergic reaction due to mast cells activation and inflammatory mediators release that induces coronary vasospasm, plaque erosion, or even stent thrombosis. A 25-year-old postpartum female with asthma and recurren...

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Autores principales:	Abdullah Haddad, Triston Smith, Aneel Bole, Moneal Shah, Mithun Chakravarthy
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2018
Materias:	allergic coronary artery syndrome coronary artery vasospasm kounis syndrome Medicine R
Acceso en línea:	https://doaj.org/article/32119b8883b74899925245c771b1c93d
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spelling	oai:doaj.org-article:32119b8883b74899925245c771b1c93d2021-12-02T16:35:54ZType I Kounis syndrome variant: A case report and literature review2231-07702249-446410.4103/ajm.AJM_114_17https://doaj.org/article/32119b8883b74899925245c771b1c93d2018-01-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/ajm.AJM_114_17https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Kounis syndrome defined as the occurrence of acute coronary syndrome in the setting of allergic reaction due to mast cells activation and inflammatory mediators release that induces coronary vasospasm, plaque erosion, or even stent thrombosis. A 25-year-old postpartum female with asthma and recurrent episodes of chest pain was admitted with ST-segment elevation myocardial infarction in the setting of coronary artery spasms. The patient was started on calcium channel blockers and nitrite-based medication with no improvement. She was noted to have eosinophilia and initiation of corticosteroid-based regimen lead to resolution of chest pain episodes and normalization of eosinophilia. Kounis syndrome should be considered in young patients with chest pain. Coronary vasodilators are considered as the first-line of treatment. The use of corticosteroids has been described in the literature in severe or refractory cases.Abdullah HaddadTriston SmithAneel BoleMoneal ShahMithun ChakravarthyThieme Medical and Scientific Publishers Pvt. Ltd.articleallergic coronary artery syndromecoronary artery vasospasmkounis syndromeMedicineRENAvicenna Journal of Medicine, Vol 8, Iss 01, Pp 37-39 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	allergic coronary artery syndrome coronary artery vasospasm kounis syndrome Medicine R
spellingShingle	allergic coronary artery syndrome coronary artery vasospasm kounis syndrome Medicine R Abdullah Haddad Triston Smith Aneel Bole Moneal Shah Mithun Chakravarthy Type I Kounis syndrome variant: A case report and literature review
description	Kounis syndrome defined as the occurrence of acute coronary syndrome in the setting of allergic reaction due to mast cells activation and inflammatory mediators release that induces coronary vasospasm, plaque erosion, or even stent thrombosis. A 25-year-old postpartum female with asthma and recurrent episodes of chest pain was admitted with ST-segment elevation myocardial infarction in the setting of coronary artery spasms. The patient was started on calcium channel blockers and nitrite-based medication with no improvement. She was noted to have eosinophilia and initiation of corticosteroid-based regimen lead to resolution of chest pain episodes and normalization of eosinophilia. Kounis syndrome should be considered in young patients with chest pain. Coronary vasodilators are considered as the first-line of treatment. The use of corticosteroids has been described in the literature in severe or refractory cases.
format	article
author	Abdullah Haddad Triston Smith Aneel Bole Moneal Shah Mithun Chakravarthy
author_facet	Abdullah Haddad Triston Smith Aneel Bole Moneal Shah Mithun Chakravarthy
author_sort	Abdullah Haddad
title	Type I Kounis syndrome variant: A case report and literature review
title_short	Type I Kounis syndrome variant: A case report and literature review
title_full	Type I Kounis syndrome variant: A case report and literature review
title_fullStr	Type I Kounis syndrome variant: A case report and literature review
title_full_unstemmed	Type I Kounis syndrome variant: A case report and literature review
title_sort	type i kounis syndrome variant: a case report and literature review
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2018
url	https://doaj.org/article/32119b8883b74899925245c771b1c93d
work_keys_str_mv	AT abdullahhaddad typeikounissyndromevariantacasereportandliteraturereview AT tristonsmith typeikounissyndromevariantacasereportandliteraturereview AT aneelbole typeikounissyndromevariantacasereportandliteraturereview AT monealshah typeikounissyndromevariantacasereportandliteraturereview AT mithunchakravarthy typeikounissyndromevariantacasereportandliteraturereview
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Type I Kounis syndrome variant: A case report and literature review

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