A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration

No effective therapies exist for dry age-related macular degeneration. In this perspective, the authors propose that research should emphasize system biology approaches that integrate various ‘omics’ data into mathematical models to establish pathogenic mechanisms on which to design novel treatments...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: James T. Handa, Cathy Bowes Rickman, Andrew D. Dick, Michael B. Gorin, Joan W. Miller, Cynthia A. Toth, Marius Ueffing, Marco Zarbin, Lindsay A. Farrer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/3214b0dbb9844fa984ecd1315c89c90d
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:No effective therapies exist for dry age-related macular degeneration. In this perspective, the authors propose that research should emphasize system biology approaches that integrate various ‘omics’ data into mathematical models to establish pathogenic mechanisms on which to design novel treatments, and identify biomarkers that predict disease progression and therapeutic response.