The communication factor EDF and the toxin-antitoxin module mazEF determine the mode of action of antibiotics.

It was recently reported that the production of Reactive Oxygen Species (ROS) is a common mechanism of cell death induced by bactericidal antibiotics. Here we show that triggering the Escherichia coli chromosomal toxin-antitoxin system mazEF is an additional determinant in the mode of action of some...

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Autores principales: Ilana Kolodkin-Gal, Boaz Sat, Alex Keshet, Hanna Engelberg-Kulka
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
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Acceso en línea:https://doaj.org/article/32235f56692046e48fef0f8af5da62f5
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