Brain-to-cervical lymph node signaling after stroke

Brain damage induces systemic inflammation, but insights and implication of this induction is still unclear. Here the authors show, using rat and mouse focal cerebral ischemia models, that the damaged brain signals via the VEGF-C/VEFGR3 axis to activate inflammatory responses in the draining cervica...

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Bibliographic Details
Main Authors: Elga Esposito, Bum Ju Ahn, Jingfei Shi, Yoshihiko Nakamura, Ji Hyun Park, Emiri T. Mandeville, Zhanyang Yu, Su Jing Chan, Rakhi Desai, Ayumi Hayakawa, Xunming Ji, Eng H. Lo, Kazuhide Hayakawa
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/3229fe5e6272458e8c1e4a8c709dd2ba
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