Screening of Keratoconus Using Autokeratometer and Keratometer Keratoconus Index

The keratometer keratoconus index (KKI) is a diagnostic index for the risk of keratoconus calculated from autokeratometer test values. We partially modified the KKI equation and assessed it without limiting the target age and severity of keratoconus. This retrospective study included 179 eyes of 99...

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Autores principales:	Takashi Kojima, Naoki Isogai, Tomoya Nishida, Tomoaki Nakamura, Kazuo Ichikawa
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	keratoconus diagnosis autokeratometer astigmatism keratometer keratoconus index (KKI) Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/3234d1d0a8644d5f9de806b56abcce44
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spelling	oai:doaj.org-article:3234d1d0a8644d5f9de806b56abcce442021-11-25T17:21:47ZScreening of Keratoconus Using Autokeratometer and Keratometer Keratoconus Index10.3390/diagnostics111121202075-4418https://doaj.org/article/3234d1d0a8644d5f9de806b56abcce442021-11-01T00:00:00Zhttps://www.mdpi.com/2075-4418/11/11/2120https://doaj.org/toc/2075-4418The keratometer keratoconus index (KKI) is a diagnostic index for the risk of keratoconus calculated from autokeratometer test values. We partially modified the KKI equation and assessed it without limiting the target age and severity of keratoconus. This retrospective study included 179 eyes of 99 patients with keratoconus and 468 eyes from 235 normal controls. In the modified KKI, oblique astigmatism or against-the-rule astigmatism was defined as ≥1D astigmatism. KKI diagnostic power was analyzed in subgroups of <50 and ≥50-year-old patients, and at different keratoconus stages. Although the sensitivity of modified KKI was comparable with that of original KKI (92.7% vs. 95.5%), modified KKI specificity was significantly higher (79.7% vs. 68.6%) (<i>p</i> = 0.0001). Using the modified KKI, sensitivity reached 100% (4/4) and specificity, 63.5% (33/52), in ≥50-year-old patients, while overall sensitivity in keratoconus ≥stage 2 was 100% (30/30). In conclusion, the modified KKI proved to be effective in keratoconus screening at all stages. However, it should be noted that false-positive frequency is higher in ≥50-year-old patients.Takashi KojimaNaoki IsogaiTomoya NishidaTomoaki NakamuraKazuo IchikawaMDPI AGarticlekeratoconusdiagnosisautokeratometerastigmatismkeratometer keratoconus index (KKI)Medicine (General)R5-920ENDiagnostics, Vol 11, Iss 2120, p 2120 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	keratoconus diagnosis autokeratometer astigmatism keratometer keratoconus index (KKI) Medicine (General) R5-920
spellingShingle	keratoconus diagnosis autokeratometer astigmatism keratometer keratoconus index (KKI) Medicine (General) R5-920 Takashi Kojima Naoki Isogai Tomoya Nishida Tomoaki Nakamura Kazuo Ichikawa Screening of Keratoconus Using Autokeratometer and Keratometer Keratoconus Index
description	The keratometer keratoconus index (KKI) is a diagnostic index for the risk of keratoconus calculated from autokeratometer test values. We partially modified the KKI equation and assessed it without limiting the target age and severity of keratoconus. This retrospective study included 179 eyes of 99 patients with keratoconus and 468 eyes from 235 normal controls. In the modified KKI, oblique astigmatism or against-the-rule astigmatism was defined as ≥1D astigmatism. KKI diagnostic power was analyzed in subgroups of <50 and ≥50-year-old patients, and at different keratoconus stages. Although the sensitivity of modified KKI was comparable with that of original KKI (92.7% vs. 95.5%), modified KKI specificity was significantly higher (79.7% vs. 68.6%) (<i>p</i> = 0.0001). Using the modified KKI, sensitivity reached 100% (4/4) and specificity, 63.5% (33/52), in ≥50-year-old patients, while overall sensitivity in keratoconus ≥stage 2 was 100% (30/30). In conclusion, the modified KKI proved to be effective in keratoconus screening at all stages. However, it should be noted that false-positive frequency is higher in ≥50-year-old patients.
format	article
author	Takashi Kojima Naoki Isogai Tomoya Nishida Tomoaki Nakamura Kazuo Ichikawa
author_facet	Takashi Kojima Naoki Isogai Tomoya Nishida Tomoaki Nakamura Kazuo Ichikawa
author_sort	Takashi Kojima
title	Screening of Keratoconus Using Autokeratometer and Keratometer Keratoconus Index
title_short	Screening of Keratoconus Using Autokeratometer and Keratometer Keratoconus Index
title_full	Screening of Keratoconus Using Autokeratometer and Keratometer Keratoconus Index
title_fullStr	Screening of Keratoconus Using Autokeratometer and Keratometer Keratoconus Index
title_full_unstemmed	Screening of Keratoconus Using Autokeratometer and Keratometer Keratoconus Index
title_sort	screening of keratoconus using autokeratometer and keratometer keratoconus index
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/3234d1d0a8644d5f9de806b56abcce44
work_keys_str_mv	AT takashikojima screeningofkeratoconususingautokeratometerandkeratometerkeratoconusindex AT naokiisogai screeningofkeratoconususingautokeratometerandkeratometerkeratoconusindex AT tomoyanishida screeningofkeratoconususingautokeratometerandkeratometerkeratoconusindex AT tomoakinakamura screeningofkeratoconususingautokeratometerandkeratometerkeratoconusindex AT kazuoichikawa screeningofkeratoconususingautokeratometerandkeratometerkeratoconusindex
_version_	1718412461242056704

Screening of Keratoconus Using Autokeratometer and Keratometer Keratoconus Index

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