Modular DNA strand-displacement controllers for directing material expansion

Materials which change shape in response to a trigger are of interest for soft robotics and targeted therapeutic delivery. Here, the authors report on the development of DNA-crosslinked hydrogels which can expand upon the detection of different biomolecular inputs mediated by DNA strand-displacement...

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Bibliographic Details
Main Authors: Joshua Fern, Rebecca Schulman
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/3241bf86890d4f8b8b342683442b1442
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Summary:Materials which change shape in response to a trigger are of interest for soft robotics and targeted therapeutic delivery. Here, the authors report on the development of DNA-crosslinked hydrogels which can expand upon the detection of different biomolecular inputs mediated by DNA strand-displacement.