Identifying topologically associating domains and subdomains by Gaussian Mixture model And Proportion test

Spatial organization of the genome plays a crucial role in regulating gene expression. Here the authors introduce GMAP, the Gaussian Mixture model And Proportion test, to identify topologically associating domains and subdomains in Hi-C data.

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Detalles Bibliográficos
Autores principales: Wenbao Yu, Bing He, Kai Tan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/324439f719804898a27e1bc7c4641b2d
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Sumario:Spatial organization of the genome plays a crucial role in regulating gene expression. Here the authors introduce GMAP, the Gaussian Mixture model And Proportion test, to identify topologically associating domains and subdomains in Hi-C data.