Identifying topologically associating domains and subdomains by Gaussian Mixture model And Proportion test
Spatial organization of the genome plays a crucial role in regulating gene expression. Here the authors introduce GMAP, the Gaussian Mixture model And Proportion test, to identify topologically associating domains and subdomains in Hi-C data.
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Nature Portfolio
2017
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oai:doaj.org-article:324439f719804898a27e1bc7c4641b2d2021-12-02T14:42:37ZIdentifying topologically associating domains and subdomains by Gaussian Mixture model And Proportion test10.1038/s41467-017-00478-82041-1723https://doaj.org/article/324439f719804898a27e1bc7c4641b2d2017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00478-8https://doaj.org/toc/2041-1723Spatial organization of the genome plays a crucial role in regulating gene expression. Here the authors introduce GMAP, the Gaussian Mixture model And Proportion test, to identify topologically associating domains and subdomains in Hi-C data.Wenbao YuBing HeKai TanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017) |
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Science Q Wenbao Yu Bing He Kai Tan Identifying topologically associating domains and subdomains by Gaussian Mixture model And Proportion test |
description |
Spatial organization of the genome plays a crucial role in regulating gene expression. Here the authors introduce GMAP, the Gaussian Mixture model And Proportion test, to identify topologically associating domains and subdomains in Hi-C data. |
format |
article |
author |
Wenbao Yu Bing He Kai Tan |
author_facet |
Wenbao Yu Bing He Kai Tan |
author_sort |
Wenbao Yu |
title |
Identifying topologically associating domains and subdomains by Gaussian Mixture model And Proportion test |
title_short |
Identifying topologically associating domains and subdomains by Gaussian Mixture model And Proportion test |
title_full |
Identifying topologically associating domains and subdomains by Gaussian Mixture model And Proportion test |
title_fullStr |
Identifying topologically associating domains and subdomains by Gaussian Mixture model And Proportion test |
title_full_unstemmed |
Identifying topologically associating domains and subdomains by Gaussian Mixture model And Proportion test |
title_sort |
identifying topologically associating domains and subdomains by gaussian mixture model and proportion test |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/324439f719804898a27e1bc7c4641b2d |
work_keys_str_mv |
AT wenbaoyu identifyingtopologicallyassociatingdomainsandsubdomainsbygaussianmixturemodelandproportiontest AT binghe identifyingtopologicallyassociatingdomainsandsubdomainsbygaussianmixturemodelandproportiontest AT kaitan identifyingtopologicallyassociatingdomainsandsubdomainsbygaussianmixturemodelandproportiontest |
_version_ |
1718389621600026624 |