Topical anti-inflammatory effect of Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves extract

Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves are leaves that contain secondary metabolites which can be developed into medicine. Ekor Naga leaves have secondary metabolite compounds of flavonoids, alkaloids, triterpenoid saponins, steroids, tannins, and phenols. This metabolite compound is...

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Autores principales:	Bernike Anatasya, Fathnur Sani K, Muhaimin Muhaimin
Formato:	article
Lenguaje:	EN
Publicado:	Universitas Ahmad Dahlan 2021
Materias:	ekor naga leaves extract anti-inflammatory leucocyte cells topical Pharmacy and materia medica RS1-441
Acceso en línea:	https://doaj.org/article/3258134234354172a55f1c3892d98f4e
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spelling	oai:doaj.org-article:3258134234354172a55f1c3892d98f4e2021-11-17T05:05:48ZTopical anti-inflammatory effect of Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves extract10.12928/pharmaciana.v11i3.176172088-45592477-0256https://doaj.org/article/3258134234354172a55f1c3892d98f4e2021-11-01T00:00:00Zhttp://journal.uad.ac.id/index.php/PHARMACIANA/article/view/17617/pdf_202https://doaj.org/toc/2088-4559https://doaj.org/toc/2477-0256Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves are leaves that contain secondary metabolites which can be developed into medicine. Ekor Naga leaves have secondary metabolite compounds of flavonoids, alkaloids, triterpenoid saponins, steroids, tannins, and phenols. This metabolite compound is the basis for testing the anti-inflammatory effect of Ekor Naga leaves extract using topical methods. The purpose of this study was to determine the anti-inflammatory effect of the ethanol extract of Ekor Naga leaves by a topical method. This study used five treatment groups with five mice in each treatment. This research tested the anti-inflammatory activity of Ekor Naga leaves extract by using the combination of 2 methods; namely the method of forming airbags and the formation of artificial edema using the induction of 2% carrageenan solution with the observation parameters being the measurement of exudate volume and differentiation of the number of leukocyte cells observed under a microscope. The results showed that the Ekor Naga leaves extract had an anti-inflammatory effect. The best inflammatory effect is a concentration of 10%, followed by a concentration of 5% and 2.5%. Bernike AnatasyaFathnur Sani KMuhaimin MuhaiminUniversitas Ahmad Dahlanarticleekor naga leaves extractanti-inflammatoryleucocyte cellstopicalPharmacy and materia medicaRS1-441ENPharmaciana, Vol 11, Iss 3, Pp 303-311 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	ekor naga leaves extract anti-inflammatory leucocyte cells topical Pharmacy and materia medica RS1-441
spellingShingle	ekor naga leaves extract anti-inflammatory leucocyte cells topical Pharmacy and materia medica RS1-441 Bernike Anatasya Fathnur Sani K Muhaimin Muhaimin Topical anti-inflammatory effect of Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves extract
description	Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves are leaves that contain secondary metabolites which can be developed into medicine. Ekor Naga leaves have secondary metabolite compounds of flavonoids, alkaloids, triterpenoid saponins, steroids, tannins, and phenols. This metabolite compound is the basis for testing the anti-inflammatory effect of Ekor Naga leaves extract using topical methods. The purpose of this study was to determine the anti-inflammatory effect of the ethanol extract of Ekor Naga leaves by a topical method. This study used five treatment groups with five mice in each treatment. This research tested the anti-inflammatory activity of Ekor Naga leaves extract by using the combination of 2 methods; namely the method of forming airbags and the formation of artificial edema using the induction of 2% carrageenan solution with the observation parameters being the measurement of exudate volume and differentiation of the number of leukocyte cells observed under a microscope. The results showed that the Ekor Naga leaves extract had an anti-inflammatory effect. The best inflammatory effect is a concentration of 10%, followed by a concentration of 5% and 2.5%.
format	article
author	Bernike Anatasya Fathnur Sani K Muhaimin Muhaimin
author_facet	Bernike Anatasya Fathnur Sani K Muhaimin Muhaimin
author_sort	Bernike Anatasya
title	Topical anti-inflammatory effect of Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves extract
title_short	Topical anti-inflammatory effect of Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves extract
title_full	Topical anti-inflammatory effect of Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves extract
title_fullStr	Topical anti-inflammatory effect of Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves extract
title_full_unstemmed	Topical anti-inflammatory effect of Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves extract
title_sort	topical anti-inflammatory effect of ekor naga (rhaphidophora pinnata (l.f) schott) leaves extract
publisher	Universitas Ahmad Dahlan
publishDate	2021
url	https://doaj.org/article/3258134234354172a55f1c3892d98f4e
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Topical anti-inflammatory effect of Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves extract

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