EXPERIMENTAL STUDY OF NOCARDIOSIS IN GUINEA PIGS

The pathology of local isolated strain of Nocardia asteroides was study in pigs . 60 animals were divided into two groups. The 1st group (40 animals) was given a single intrapulmonary of 3.3X10'CFU of N. astoroides. The 2 nd group (20 animals) served as control . Eight animals died during the...

Full description

Saved in:
Bibliographic Details
Main Author: M. J. ALWAN
Format: article
Language:EN
Published: University of Baghdad, College of Veterinary Medicine 2000
Subjects:
Online Access:https://doaj.org/article/326a4d96e0d44b88bc1c2454b070b1ea
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The pathology of local isolated strain of Nocardia asteroides was study in pigs . 60 animals were divided into two groups. The 1st group (40 animals) was given a single intrapulmonary of 3.3X10'CFU of N. astoroides. The 2 nd group (20 animals) served as control . Eight animals died during the first 3 weeks post – infection while the remaining were sacrificed at 6, 12, 24, 48 hrs and 4, 8, 16, 24 and 62 days P.I. Early pathological examination revealed acute suppurative changes which seen turned into disseminated chronic form. Pyogranul matous and epithelioid granuloma have represented the main pathological changes at 8-24 days P.J. The results revealed arisein the level of bacterial counts followed by drop in count within 8-24 days P.I. Excepted kidney in which high bacterial counts persisted toward the end of the experiment