Evaluation of the OsTIR1 and AtAFB2 AID Systems for Genome Architectural Protein Degradation in Mammalian Cells

The auxin-inducible degron (AID) system is a promising tool for dynamic protein degradation. In mammalian cells, this approach has become indispensable to study fundamental molecular functions, such as replication, chromatin dynamics, or transcription, which are otherwise difficult to dissect. We pr...

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Main Authors: Anastasia Yunusova, Alexander Smirnov, Tatiana Shnaider, Varvara Lukyanchikova, Svetlana Afonnikova, Nariman Battulin
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
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Online Access:https://doaj.org/article/326ad3447e7448588d75862d96e9e9d8
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