Chronic Autoimmune Gastritis: Modern Diagnostic Principles
This article summarizes and systematizes the available data from the literature on chronic autoimmune gastritis (CAG) in order to increase the awareness of specialists about the modern possibilities for diagnosing the disease, including its early stages. The clinical manifestation of the disease inc...
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MDPI AG
2021
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oai:doaj.org-article:327d0236ae234c30ab5f6878698c28382021-11-25T17:21:44ZChronic Autoimmune Gastritis: Modern Diagnostic Principles10.3390/diagnostics111121132075-4418https://doaj.org/article/327d0236ae234c30ab5f6878698c28382021-11-01T00:00:00Zhttps://www.mdpi.com/2075-4418/11/11/2113https://doaj.org/toc/2075-4418This article summarizes and systematizes the available data from the literature on chronic autoimmune gastritis (CAG) in order to increase the awareness of specialists about the modern possibilities for diagnosing the disease, including its early stages. The clinical manifestation of the disease includes possible variants such as gastrointestinal, hematological (first of all, the formation of iron deficiency and B12-deficiency anemia), and neurological variants. Patients with chronic autoimmune gastritis are characterized by comorbidity with other autoimmune diseases. In this paper, data on the most informative serological markers for the diagnosis of CAG, as well as laboratory tests to detect micronutrient deficiencies, information on the characteristic changes in the gastric mucosa, and the prognosis of the disease, are presented. The diagnosis of CAG should be based on a multidisciplinary approach that combines a thorough analysis of a patient’s complaints with a mandatory assessment of nutritional status, as well as the results of serological, endoscopic, and histological research methods.Maria A. LivzanOlga V. GausSergei I. MozgovoiDmitry S. BordinMDPI AGarticlechronic autoimmune gastritisatrophic gastritisnutritional statusvitamin B12 deficiencymegaloblastic anemianeuroendocrine tumorsMedicine (General)R5-920ENDiagnostics, Vol 11, Iss 2113, p 2113 (2021) |
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chronic autoimmune gastritis atrophic gastritis nutritional status vitamin B12 deficiency megaloblastic anemia neuroendocrine tumors Medicine (General) R5-920 |
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chronic autoimmune gastritis atrophic gastritis nutritional status vitamin B12 deficiency megaloblastic anemia neuroendocrine tumors Medicine (General) R5-920 Maria A. Livzan Olga V. Gaus Sergei I. Mozgovoi Dmitry S. Bordin Chronic Autoimmune Gastritis: Modern Diagnostic Principles |
description |
This article summarizes and systematizes the available data from the literature on chronic autoimmune gastritis (CAG) in order to increase the awareness of specialists about the modern possibilities for diagnosing the disease, including its early stages. The clinical manifestation of the disease includes possible variants such as gastrointestinal, hematological (first of all, the formation of iron deficiency and B12-deficiency anemia), and neurological variants. Patients with chronic autoimmune gastritis are characterized by comorbidity with other autoimmune diseases. In this paper, data on the most informative serological markers for the diagnosis of CAG, as well as laboratory tests to detect micronutrient deficiencies, information on the characteristic changes in the gastric mucosa, and the prognosis of the disease, are presented. The diagnosis of CAG should be based on a multidisciplinary approach that combines a thorough analysis of a patient’s complaints with a mandatory assessment of nutritional status, as well as the results of serological, endoscopic, and histological research methods. |
format |
article |
author |
Maria A. Livzan Olga V. Gaus Sergei I. Mozgovoi Dmitry S. Bordin |
author_facet |
Maria A. Livzan Olga V. Gaus Sergei I. Mozgovoi Dmitry S. Bordin |
author_sort |
Maria A. Livzan |
title |
Chronic Autoimmune Gastritis: Modern Diagnostic Principles |
title_short |
Chronic Autoimmune Gastritis: Modern Diagnostic Principles |
title_full |
Chronic Autoimmune Gastritis: Modern Diagnostic Principles |
title_fullStr |
Chronic Autoimmune Gastritis: Modern Diagnostic Principles |
title_full_unstemmed |
Chronic Autoimmune Gastritis: Modern Diagnostic Principles |
title_sort |
chronic autoimmune gastritis: modern diagnostic principles |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doaj.org/article/327d0236ae234c30ab5f6878698c2838 |
work_keys_str_mv |
AT mariaalivzan chronicautoimmunegastritismoderndiagnosticprinciples AT olgavgaus chronicautoimmunegastritismoderndiagnosticprinciples AT sergeiimozgovoi chronicautoimmunegastritismoderndiagnosticprinciples AT dmitrysbordin chronicautoimmunegastritismoderndiagnosticprinciples |
_version_ |
1718412461434994688 |