Activation of LXRα improves cardiac remodeling induced by pulmonary artery hypertension in rats

Abstract Inflammatory factors regulated by NF-κB play a significant role in PAH and myocardial hypertrophy. LXR activation may inhibit myocardial hypertrophy via suppressing inflammatory pathways; it is unknown whether LXR is also involved in PAH-induced myocardial hypertrophy or remodeling. To furt...

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Autores principales: Yibo Gong, Yifeng Yang, Qin Wu, Ge Gao, Yin Liu, Yaoyao Xiong, Can Huang, Sijie Wu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/327d5ef72998436da400ac45e5e076fc
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