Role of cross-cleft contacts in NMDA receptor gating.
In response to brief glutamate exposure, NMDA receptors produce excitatory currents that have sub-maximal amplitudes and characteristically slow kinetics. The activation sequence starts when glutamate binds to residues located on the upper lobe of extracellularly located ligand-binding domains (LBDs...
Guardado en:
Autores principales: | Meaghan A Paganelli, Cassandra L Kussius, Gabriela K Popescu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/32838e0657084d0e85616958e8679ebc |
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