Baseline Predictive Factors of Visual Outcome and Persistence of Subretinal Fluid Based on Morphologic Changes in Spectral Domain Optical Coherence Tomography in Patients with Idiopathic Central Serous Chorioretinopathy

Barsha Suwal,1 Deepak Khadka,1 Arjun Shrestha,1 Sangeeta Shrestha,1 Nirsara Shrestha,1 Bijay Khatri2 1Department of Ophthalmology, BP Eye Foundation, Hospital for Children, Eye, ENT and Rehabilitation Services (CHEERS), Lokanthali, Bhaktapur, Nepal; 2Department of Academics and Research, Hospital fo...

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Autores principales:	Suwal B, Khadka D, Shrestha A, Shrestha S, Shrestha N, Khatri B
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	central serous chorioretinopathy optical coherence tomography visual outcome persistent subretinal fluid Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/3283ded5a3a94f639e93c078533c97a2
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spelling	oai:doaj.org-article:3283ded5a3a94f639e93c078533c97a22021-12-02T05:20:16ZBaseline Predictive Factors of Visual Outcome and Persistence of Subretinal Fluid Based on Morphologic Changes in Spectral Domain Optical Coherence Tomography in Patients with Idiopathic Central Serous Chorioretinopathy1177-5483https://doaj.org/article/3283ded5a3a94f639e93c078533c97a22019-12-01T00:00:00Zhttps://www.dovepress.com/baseline-predictive-factors-of-visual-outcome-and-persistence-of-subre-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Barsha Suwal,1 Deepak Khadka,1 Arjun Shrestha,1 Sangeeta Shrestha,1 Nirsara Shrestha,1 Bijay Khatri2 1Department of Ophthalmology, BP Eye Foundation, Hospital for Children, Eye, ENT and Rehabilitation Services (CHEERS), Lokanthali, Bhaktapur, Nepal; 2Department of Academics and Research, Hospital for Children, Eye, ENT, Rehabilitation Services (CHEERS), Lokanthali, Bhaktapur, NepalCorrespondence: Barsha SuwalDepartment of Ophthalmology, BP Eye Foundation, Hospital for Children, Eye, ENT and Rehabilitation Services (CHEERS), Lokanthali, Bhaktapur, NepalTel +977-9803056313Fax +977-16639735 Email suwal.barsha@gmail.comBackground: To determine the influence of spectral domain optical coherence tomography (OCT) changes on visual outcome and persistence of subretinal fluid (SRF) in patients with idiopathic central serous chorioretinopathy (CSCR).Materials and methods: In a retrospective study done in 48 eyes of 45 patients diagnosed as CSCR, all eyes were subjected to fundus photography, spectral domain OCT, and fluorescein angiography (FA) in selected cases.Results: Retinal pigment epithelium detachment was present in 22.91% of the cases at presentation. The logMar best corrected visual acuity improved from 0.46±0.29 at presentation to 0.18±0.22 at 3 months (P-value<0.01). The mean foveal thickness was 486.81±146.06 μm at presentation and 259±94.5 μm at 3 months (P-value<0.01) (paired T-test). OCT factors that were associated with poor visual outcome (BCVA>0.3 logMar) were disruption in the inner segment (IS)/outer segment (OS) junction or external limiting membrane (ELM) line and hyper-reflective dots in the intra/subretinal layer (P-value<0.05) (Fischer’s Exact test). Out of the total 48 eyes, 26 had persistent SRF at 3 months. The presence of discontinuation in IS/OS junction and hyper-reflective dots in the intra/subretinal layer were the only two OCT factors that were associated with the persistence of SRF (P-value<0.01) (Pearson’s Chi-square test).Conclusion: Visual outcome and persistence of subretinal fluid at 3 months can be predicted on the basis of early morphologic changes in OCT. This will aid in counseling patients regarding its course and may guide us in its management.Keywords: central serous chorioretinopathy, optical coherence tomography, visual outcome, persistent subretinal fluidSuwal BKhadka DShrestha AShrestha SShrestha NKhatri BDove Medical Pressarticlecentral serous chorioretinopathyoptical coherence tomographyvisual outcomepersistent subretinal fluidOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 13, Pp 2439-2444 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	central serous chorioretinopathy optical coherence tomography visual outcome persistent subretinal fluid Ophthalmology RE1-994
spellingShingle	central serous chorioretinopathy optical coherence tomography visual outcome persistent subretinal fluid Ophthalmology RE1-994 Suwal B Khadka D Shrestha A Shrestha S Shrestha N Khatri B Baseline Predictive Factors of Visual Outcome and Persistence of Subretinal Fluid Based on Morphologic Changes in Spectral Domain Optical Coherence Tomography in Patients with Idiopathic Central Serous Chorioretinopathy
description	Barsha Suwal,1 Deepak Khadka,1 Arjun Shrestha,1 Sangeeta Shrestha,1 Nirsara Shrestha,1 Bijay Khatri2 1Department of Ophthalmology, BP Eye Foundation, Hospital for Children, Eye, ENT and Rehabilitation Services (CHEERS), Lokanthali, Bhaktapur, Nepal; 2Department of Academics and Research, Hospital for Children, Eye, ENT, Rehabilitation Services (CHEERS), Lokanthali, Bhaktapur, NepalCorrespondence: Barsha SuwalDepartment of Ophthalmology, BP Eye Foundation, Hospital for Children, Eye, ENT and Rehabilitation Services (CHEERS), Lokanthali, Bhaktapur, NepalTel +977-9803056313Fax +977-16639735 Email suwal.barsha@gmail.comBackground: To determine the influence of spectral domain optical coherence tomography (OCT) changes on visual outcome and persistence of subretinal fluid (SRF) in patients with idiopathic central serous chorioretinopathy (CSCR).Materials and methods: In a retrospective study done in 48 eyes of 45 patients diagnosed as CSCR, all eyes were subjected to fundus photography, spectral domain OCT, and fluorescein angiography (FA) in selected cases.Results: Retinal pigment epithelium detachment was present in 22.91% of the cases at presentation. The logMar best corrected visual acuity improved from 0.46±0.29 at presentation to 0.18±0.22 at 3 months (P-value<0.01). The mean foveal thickness was 486.81±146.06 μm at presentation and 259±94.5 μm at 3 months (P-value<0.01) (paired T-test). OCT factors that were associated with poor visual outcome (BCVA>0.3 logMar) were disruption in the inner segment (IS)/outer segment (OS) junction or external limiting membrane (ELM) line and hyper-reflective dots in the intra/subretinal layer (P-value<0.05) (Fischer’s Exact test). Out of the total 48 eyes, 26 had persistent SRF at 3 months. The presence of discontinuation in IS/OS junction and hyper-reflective dots in the intra/subretinal layer were the only two OCT factors that were associated with the persistence of SRF (P-value<0.01) (Pearson’s Chi-square test).Conclusion: Visual outcome and persistence of subretinal fluid at 3 months can be predicted on the basis of early morphologic changes in OCT. This will aid in counseling patients regarding its course and may guide us in its management.Keywords: central serous chorioretinopathy, optical coherence tomography, visual outcome, persistent subretinal fluid
format	article
author	Suwal B Khadka D Shrestha A Shrestha S Shrestha N Khatri B
author_facet	Suwal B Khadka D Shrestha A Shrestha S Shrestha N Khatri B
author_sort	Suwal B
title	Baseline Predictive Factors of Visual Outcome and Persistence of Subretinal Fluid Based on Morphologic Changes in Spectral Domain Optical Coherence Tomography in Patients with Idiopathic Central Serous Chorioretinopathy
title_short	Baseline Predictive Factors of Visual Outcome and Persistence of Subretinal Fluid Based on Morphologic Changes in Spectral Domain Optical Coherence Tomography in Patients with Idiopathic Central Serous Chorioretinopathy
title_full	Baseline Predictive Factors of Visual Outcome and Persistence of Subretinal Fluid Based on Morphologic Changes in Spectral Domain Optical Coherence Tomography in Patients with Idiopathic Central Serous Chorioretinopathy
title_fullStr	Baseline Predictive Factors of Visual Outcome and Persistence of Subretinal Fluid Based on Morphologic Changes in Spectral Domain Optical Coherence Tomography in Patients with Idiopathic Central Serous Chorioretinopathy
title_full_unstemmed	Baseline Predictive Factors of Visual Outcome and Persistence of Subretinal Fluid Based on Morphologic Changes in Spectral Domain Optical Coherence Tomography in Patients with Idiopathic Central Serous Chorioretinopathy
title_sort	baseline predictive factors of visual outcome and persistence of subretinal fluid based on morphologic changes in spectral domain optical coherence tomography in patients with idiopathic central serous chorioretinopathy
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/3283ded5a3a94f639e93c078533c97a2
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Baseline Predictive Factors of Visual Outcome and Persistence of Subretinal Fluid Based on Morphologic Changes in Spectral Domain Optical Coherence Tomography in Patients with Idiopathic Central Serous Chorioretinopathy

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