Clinical characteristics and chest computed tomography findings related to the infectivity of pulmonary tuberculosis

Abstract Aim This study mainly evaluates the clinical characteristics and chest chest computed tomography (CT) findings of AFB-positive and AFB-negative pulmonary tuberculosis (PTB) patients to explore the relationship between AFB-positive and clinico-radiological findings. Methods A retrospective a...

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Autores principales:	Yuanyuan Wang, Xiaoqian Shang, Liang Wang, Jiahui Fan, Fengming Tian, Xuanzheng Wang, Weina Kong, Jing Wang, Yunling Wang, Xiumin Ma
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Pulmonary tuberculosis Acid-fast bacilli-negative Acid-fast bacilli-positive Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/328605f111a74b5aa7389410b62ff7e3
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spelling	oai:doaj.org-article:328605f111a74b5aa7389410b62ff7e32021-11-28T12:41:57ZClinical characteristics and chest computed tomography findings related to the infectivity of pulmonary tuberculosis10.1186/s12879-021-06901-21471-2334https://doaj.org/article/328605f111a74b5aa7389410b62ff7e32021-11-01T00:00:00Zhttps://doi.org/10.1186/s12879-021-06901-2https://doaj.org/toc/1471-2334Abstract Aim This study mainly evaluates the clinical characteristics and chest chest computed tomography (CT) findings of AFB-positive and AFB-negative pulmonary tuberculosis (PTB) patients to explore the relationship between AFB-positive and clinico-radiological findings. Methods A retrospective analysis of 224 hospitalized tuberculosis patients from 2018 to 2020 was undertaken. According to the AFB smear results, they were divided into AFB-positive pulmonary tuberculosis (positive by Ziehl–Neelsen staining) and AFB-negative pulmonary tuberculosis and patients’ CT results and laboratory test results were analyzed. Results A total of 224 PTB patients were enrolled. AFB-positive (n = 94, 42%) and AFB-negative (n = 130, 58%). AFB-positive patients had more consolidation (77.7% vs. 53.8%, p < 0.01), cavity (55.3% vs. 34.6%, p < 0.01), calcification (38.3% vs. 20%, p < 0.01), bronchiectasis (7.5% vs. 1.5%, p < 0.05), bronchiarctia (6.4% vs. 0.8%, p < 0.05), and right upper lobe involvement (57.5% vs. 33.1%, p < 0.01), left upper lobe involvement (46.8% vs. 33.1%, p < 0.05) and lymphadenopathy (58.5% vs. 37.7%, p < 0.01). Conclusion The study found that when pulmonary tuberculosis patients have consolidation, cavity, upper lobe involvement and lymphadenopathy on chest CT images, they may have a higher risk of AFB-positive tuberculosis.Yuanyuan WangXiaoqian ShangLiang WangJiahui FanFengming TianXuanzheng WangWeina KongJing WangYunling WangXiumin MaBMCarticlePulmonary tuberculosisAcid-fast bacilli-negativeAcid-fast bacilli-positiveInfectious and parasitic diseasesRC109-216ENBMC Infectious Diseases, Vol 21, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Pulmonary tuberculosis Acid-fast bacilli-negative Acid-fast bacilli-positive Infectious and parasitic diseases RC109-216
spellingShingle	Pulmonary tuberculosis Acid-fast bacilli-negative Acid-fast bacilli-positive Infectious and parasitic diseases RC109-216 Yuanyuan Wang Xiaoqian Shang Liang Wang Jiahui Fan Fengming Tian Xuanzheng Wang Weina Kong Jing Wang Yunling Wang Xiumin Ma Clinical characteristics and chest computed tomography findings related to the infectivity of pulmonary tuberculosis
description	Abstract Aim This study mainly evaluates the clinical characteristics and chest chest computed tomography (CT) findings of AFB-positive and AFB-negative pulmonary tuberculosis (PTB) patients to explore the relationship between AFB-positive and clinico-radiological findings. Methods A retrospective analysis of 224 hospitalized tuberculosis patients from 2018 to 2020 was undertaken. According to the AFB smear results, they were divided into AFB-positive pulmonary tuberculosis (positive by Ziehl–Neelsen staining) and AFB-negative pulmonary tuberculosis and patients’ CT results and laboratory test results were analyzed. Results A total of 224 PTB patients were enrolled. AFB-positive (n = 94, 42%) and AFB-negative (n = 130, 58%). AFB-positive patients had more consolidation (77.7% vs. 53.8%, p < 0.01), cavity (55.3% vs. 34.6%, p < 0.01), calcification (38.3% vs. 20%, p < 0.01), bronchiectasis (7.5% vs. 1.5%, p < 0.05), bronchiarctia (6.4% vs. 0.8%, p < 0.05), and right upper lobe involvement (57.5% vs. 33.1%, p < 0.01), left upper lobe involvement (46.8% vs. 33.1%, p < 0.05) and lymphadenopathy (58.5% vs. 37.7%, p < 0.01). Conclusion The study found that when pulmonary tuberculosis patients have consolidation, cavity, upper lobe involvement and lymphadenopathy on chest CT images, they may have a higher risk of AFB-positive tuberculosis.
format	article
author	Yuanyuan Wang Xiaoqian Shang Liang Wang Jiahui Fan Fengming Tian Xuanzheng Wang Weina Kong Jing Wang Yunling Wang Xiumin Ma
author_facet	Yuanyuan Wang Xiaoqian Shang Liang Wang Jiahui Fan Fengming Tian Xuanzheng Wang Weina Kong Jing Wang Yunling Wang Xiumin Ma
author_sort	Yuanyuan Wang
title	Clinical characteristics and chest computed tomography findings related to the infectivity of pulmonary tuberculosis
title_short	Clinical characteristics and chest computed tomography findings related to the infectivity of pulmonary tuberculosis
title_full	Clinical characteristics and chest computed tomography findings related to the infectivity of pulmonary tuberculosis
title_fullStr	Clinical characteristics and chest computed tomography findings related to the infectivity of pulmonary tuberculosis
title_full_unstemmed	Clinical characteristics and chest computed tomography findings related to the infectivity of pulmonary tuberculosis
title_sort	clinical characteristics and chest computed tomography findings related to the infectivity of pulmonary tuberculosis
publisher	BMC
publishDate	2021
url	https://doaj.org/article/328605f111a74b5aa7389410b62ff7e3
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Clinical characteristics and chest computed tomography findings related to the infectivity of pulmonary tuberculosis

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