Associated factors with recurrent wheezing in infants: is there difference between the sexes?

Associated factors with recurrent wheezing in infants: is there difference between the sexes?

Objective: Identify associated factors for recurrent wheezing (RW) in male and female infants. Methods: Cross-sectional multicentric study using the standardized questionnaire from the Estudio Internacional sobre Sibilancias en Lactantes (EISL). The questionnaire was applied to parents of 9345 infan...

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Autores principales: Wellington Fernando da Silva Ferreira, Denise Siqueira de Carvalho, Gustavo Falbo Wandalsen, Dirceu Solé, Emanuel Sávio Cavalcante Sarinho, Décio Medeiros, Ana Carolina Cavalcanti Dela Bianca Melo, Elaine Xavier Prestes, Paulo Augusto Moreira Camargos, Karin Regina Luhm, Luis Garcia-Marcos, Javier Mallol, Nelson Augusto Rosário, Herberto José Chong-Neto
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Wheezing
Risk factors
Infants
Sex
Pediatrics
RJ1-570
Acceso en línea:https://doaj.org/article/328adc61c2f04a61841aec730fdfe220
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Sumario:Objective: Identify associated factors for recurrent wheezing (RW) in male and female infants. Methods: Cross-sectional multicentric study using the standardized questionnaire from the Estudio Internacional sobre Sibilancias en Lactantes (EISL). The questionnaire was applied to parents of 9345 infants aged 12–15 months at the time of immunization/routine visits. Results: One thousand two hundred and sixty-one (13.5%) males and nine hundred sixty-three (10.3%) females have had RW (≥3 episodes), respectively (p10 colds episodes (OR = 3.46; IC 95% 2.35–5.07), air pollution (OR = 1.33; IC 95% 1.12–1.59), molds at home (OR = 1.23; IC 95% 1.03–1.47), Afro-descendants (OR = 1.42; IC 95% 1.20–1.69), bronchopneumonia (OR = 1.41; IC; 1.11–1.78), severe episodes of wheezing in the first year (OR = 1.56; IC 95% 1.29–1.89), treatment with bronchodilators (OR = 1.60; IC 95% 1.22–2,1) and treatment with oral corticosteroids (OR = 1,23; IC 95% 0.99–1,52). Associated factors for RW for females were passive smoking (OR = 1.24; IC 95% 1.01−1,51), parents diagnosed with asthma (OR = 1.32; IC 95% 1,08−1,62), parents with allergic rhinitis (OR = 1.26; IC 95% 1.04–1.53), daycare attendance (OR = 1.48; IC 95% 1.17−1,88), colds in the first 6 months of life (OR = 2.19; IC 95% 1.69–2.82), personal diagnosis of asthma (OR = 1.84; IC 95% 1.39–2.44), emergency room visits (OR = 1.78; IC 95% 1.44–2.21), nighttime symptoms (OR = 2.89; IC 95% 2.34–3.53) and updated immunization (OR = 0.62; IC 95% 0.41−0.96). Conclusion: There are differences in associated factors for RW between genders. Identification of these differences could be useful to the approach and management of RW between boys and girls.

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