Comparing the Effects of Vacuum Constrictive Devices and Intra-Cavernosal Injection of Papaverine for Erectile Dysfunction Treatment

Introduction: For erectile dysfunction (ED) treatment, Vacuum therapy (VT) utilizes negative pressure to distend the corporal sinusoids and to increase the blood inflow to the penis. In the current study, we evaluated the vacuum constrictive device (VCD) and intracavernosal injection (ICI) of papave...

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Autores principales:	Amir Ghasemlouei, Feraidoon Khayyamfar, Seyed Kazem Forootan, Amir Mahdi Khayyamfar, Masood Vahdani
Formato:	article
Lenguaje:	EN
Publicado:	Urology Research Center 2021
Materias:	erectile dysfunction papaverine vacuum constrictive device intracavernosal injection Diseases of the genitourinary system. Urology RC870-923
Acceso en línea:	https://doaj.org/article/32978572669a4b18a76d2cc6436883d1
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spelling	oai:doaj.org-article:32978572669a4b18a76d2cc6436883d12021-11-30T07:27:07ZComparing the Effects of Vacuum Constrictive Devices and Intra-Cavernosal Injection of Papaverine for Erectile Dysfunction Treatment10.22034/TRU.2021.292902.10702717-042Xhttps://doaj.org/article/32978572669a4b18a76d2cc6436883d12021-07-01T00:00:00Zhttps://www.transresurology.com/article_132982.htmlhttps://doaj.org/toc/2717-042XIntroduction: For erectile dysfunction (ED) treatment, Vacuum therapy (VT) utilizes negative pressure to distend the corporal sinusoids and to increase the blood inflow to the penis. In the current study, we evaluated the vacuum constrictive device (VCD) and intracavernosal injection (ICI) of papaverine for the treatment of ED. Methods: A total number of 80 erectile dysfunctions (ED) were divided into 4 groups of 20 couples. The first group was treated with Papaverine who had a virgin wife (a). The second group was unconsummated marriage couples who were treated with vacuums (b). The third group was and the couples with experience of sexual intercourse who had been treated with Papaverine injection (c). The fourth group was the couples with experience of sexual intercourse that were treated with a vacuum device (d). Results: After 4 months of treatment, all patients were able to have sex. In the unconsummated couples group treated with papaverine and consummated couples treated with papaverine, all of the indicators of the erectile function were significantly increased compared to pre-treatment (p-value<0.05). There were no significant differences between the two methods in terms of other complications such as ecchymosis, blisters, headache, cutaneous rash, and vaso-vascular shock (p-value>0.05). Conclusions: This study showed that in patients with erectile dysfunction who are having virgin spouses and who are not responding to the first line of oral medication that 5-inhibitors phosphodiesterase can be the excellent candidate for ICI of vasoactive drugs therapy.Amir GhasemloueiFeraidoon KhayyamfarSeyed Kazem Forootan Amir Mahdi Khayyamfar Masood VahdaniUrology Research Centerarticleerectile dysfunctionpapaverinevacuum constrictive deviceintracavernosal injectionDiseases of the genitourinary system. UrologyRC870-923ENTranslational Research in Urology, Vol 3, Iss 2, Pp 74-80 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	erectile dysfunction papaverine vacuum constrictive device intracavernosal injection Diseases of the genitourinary system. Urology RC870-923
spellingShingle	erectile dysfunction papaverine vacuum constrictive device intracavernosal injection Diseases of the genitourinary system. Urology RC870-923 Amir Ghasemlouei Feraidoon Khayyamfar Seyed Kazem Forootan Amir Mahdi Khayyamfar Masood Vahdani Comparing the Effects of Vacuum Constrictive Devices and Intra-Cavernosal Injection of Papaverine for Erectile Dysfunction Treatment
description	Introduction: For erectile dysfunction (ED) treatment, Vacuum therapy (VT) utilizes negative pressure to distend the corporal sinusoids and to increase the blood inflow to the penis. In the current study, we evaluated the vacuum constrictive device (VCD) and intracavernosal injection (ICI) of papaverine for the treatment of ED. Methods: A total number of 80 erectile dysfunctions (ED) were divided into 4 groups of 20 couples. The first group was treated with Papaverine who had a virgin wife (a). The second group was unconsummated marriage couples who were treated with vacuums (b). The third group was and the couples with experience of sexual intercourse who had been treated with Papaverine injection (c). The fourth group was the couples with experience of sexual intercourse that were treated with a vacuum device (d). Results: After 4 months of treatment, all patients were able to have sex. In the unconsummated couples group treated with papaverine and consummated couples treated with papaverine, all of the indicators of the erectile function were significantly increased compared to pre-treatment (p-value<0.05). There were no significant differences between the two methods in terms of other complications such as ecchymosis, blisters, headache, cutaneous rash, and vaso-vascular shock (p-value>0.05). Conclusions: This study showed that in patients with erectile dysfunction who are having virgin spouses and who are not responding to the first line of oral medication that 5-inhibitors phosphodiesterase can be the excellent candidate for ICI of vasoactive drugs therapy.
format	article
author	Amir Ghasemlouei Feraidoon Khayyamfar Seyed Kazem Forootan Amir Mahdi Khayyamfar Masood Vahdani
author_facet	Amir Ghasemlouei Feraidoon Khayyamfar Seyed Kazem Forootan Amir Mahdi Khayyamfar Masood Vahdani
author_sort	Amir Ghasemlouei
title	Comparing the Effects of Vacuum Constrictive Devices and Intra-Cavernosal Injection of Papaverine for Erectile Dysfunction Treatment
title_short	Comparing the Effects of Vacuum Constrictive Devices and Intra-Cavernosal Injection of Papaverine for Erectile Dysfunction Treatment
title_full	Comparing the Effects of Vacuum Constrictive Devices and Intra-Cavernosal Injection of Papaverine for Erectile Dysfunction Treatment
title_fullStr	Comparing the Effects of Vacuum Constrictive Devices and Intra-Cavernosal Injection of Papaverine for Erectile Dysfunction Treatment
title_full_unstemmed	Comparing the Effects of Vacuum Constrictive Devices and Intra-Cavernosal Injection of Papaverine for Erectile Dysfunction Treatment
title_sort	comparing the effects of vacuum constrictive devices and intra-cavernosal injection of papaverine for erectile dysfunction treatment
publisher	Urology Research Center
publishDate	2021
url	https://doaj.org/article/32978572669a4b18a76d2cc6436883d1
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Comparing the Effects of Vacuum Constrictive Devices and Intra-Cavernosal Injection of Papaverine for Erectile Dysfunction Treatment

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