Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection

Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection

Influenza A virus (IAV) infection can be exacerbated by bacterial co-infections but the effect of IAV on the upper respiratory tract (URT) microbiome remains unclear. Here, the authors compare the dynamics of the UTR microbiome in IAV-infected ferrets and humans, finding similar trends at the ecosys...

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Autores principales: Drishti Kaul, Raveen Rathnasinghe, Marcela Ferres, Gene S. Tan, Aldo Barrera, Brett E. Pickett, Barbara A. Methe, Suman R. Das, Isolda Budnik, Rebecca A. Halpin, David Wentworth, Mirco Schmolke, Ignacio Mena, Randy A. Albrecht, Indresh Singh, Karen E. Nelson, Adolfo García-Sastre, Chris L. Dupont, Rafael A. Medina
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/329c0d9296a64098bb0377bc1dba8680
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Sumario:Influenza A virus (IAV) infection can be exacerbated by bacterial co-infections but the effect of IAV on the upper respiratory tract (URT) microbiome remains unclear. Here, the authors compare the dynamics of the UTR microbiome in IAV-infected ferrets and humans, finding similar trends at the ecosystem and individual taxon level in both hosts.

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