Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection

Influenza A virus (IAV) infection can be exacerbated by bacterial co-infections but the effect of IAV on the upper respiratory tract (URT) microbiome remains unclear. Here, the authors compare the dynamics of the UTR microbiome in IAV-infected ferrets and humans, finding similar trends at the ecosys...

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Autores principales: Drishti Kaul, Raveen Rathnasinghe, Marcela Ferres, Gene S. Tan, Aldo Barrera, Brett E. Pickett, Barbara A. Methe, Suman R. Das, Isolda Budnik, Rebecca A. Halpin, David Wentworth, Mirco Schmolke, Ignacio Mena, Randy A. Albrecht, Indresh Singh, Karen E. Nelson, Adolfo García-Sastre, Chris L. Dupont, Rafael A. Medina
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/329c0d9296a64098bb0377bc1dba8680
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spelling oai:doaj.org-article:329c0d9296a64098bb0377bc1dba86802021-12-02T14:58:51ZMicrobiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection10.1038/s41467-020-16429-92041-1723https://doaj.org/article/329c0d9296a64098bb0377bc1dba86802020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16429-9https://doaj.org/toc/2041-1723Influenza A virus (IAV) infection can be exacerbated by bacterial co-infections but the effect of IAV on the upper respiratory tract (URT) microbiome remains unclear. Here, the authors compare the dynamics of the UTR microbiome in IAV-infected ferrets and humans, finding similar trends at the ecosystem and individual taxon level in both hosts.Drishti KaulRaveen RathnasingheMarcela FerresGene S. TanAldo BarreraBrett E. PickettBarbara A. MetheSuman R. DasIsolda BudnikRebecca A. HalpinDavid WentworthMirco SchmolkeIgnacio MenaRandy A. AlbrechtIndresh SinghKaren E. NelsonAdolfo García-SastreChris L. DupontRafael A. MedinaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Drishti Kaul
Raveen Rathnasinghe
Marcela Ferres
Gene S. Tan
Aldo Barrera
Brett E. Pickett
Barbara A. Methe
Suman R. Das
Isolda Budnik
Rebecca A. Halpin
David Wentworth
Mirco Schmolke
Ignacio Mena
Randy A. Albrecht
Indresh Singh
Karen E. Nelson
Adolfo García-Sastre
Chris L. Dupont
Rafael A. Medina
Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection
description Influenza A virus (IAV) infection can be exacerbated by bacterial co-infections but the effect of IAV on the upper respiratory tract (URT) microbiome remains unclear. Here, the authors compare the dynamics of the UTR microbiome in IAV-infected ferrets and humans, finding similar trends at the ecosystem and individual taxon level in both hosts.
format article
author Drishti Kaul
Raveen Rathnasinghe
Marcela Ferres
Gene S. Tan
Aldo Barrera
Brett E. Pickett
Barbara A. Methe
Suman R. Das
Isolda Budnik
Rebecca A. Halpin
David Wentworth
Mirco Schmolke
Ignacio Mena
Randy A. Albrecht
Indresh Singh
Karen E. Nelson
Adolfo García-Sastre
Chris L. Dupont
Rafael A. Medina
author_facet Drishti Kaul
Raveen Rathnasinghe
Marcela Ferres
Gene S. Tan
Aldo Barrera
Brett E. Pickett
Barbara A. Methe
Suman R. Das
Isolda Budnik
Rebecca A. Halpin
David Wentworth
Mirco Schmolke
Ignacio Mena
Randy A. Albrecht
Indresh Singh
Karen E. Nelson
Adolfo García-Sastre
Chris L. Dupont
Rafael A. Medina
author_sort Drishti Kaul
title Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection
title_short Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection
title_full Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection
title_fullStr Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection
title_full_unstemmed Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection
title_sort microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza a virus infection
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/329c0d9296a64098bb0377bc1dba8680
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