White blood cell-based detection of asymptomatic scrapie infection by ex vivo assays.

Prion transmission can occur by blood transfusion in human variant Creutzfeldt-Jakob disease and in experimental animal models, including sheep. Screening of blood and its derivatives for the presence of prions became therefore a major public health issue. As infectious titer in blood is reportedly...

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Main Authors: Sophie Halliez, Emilie Jaumain, Alvina Huor, Jean-Yves Douet, Séverine Lugan, Hervé Cassard, Caroline Lacroux, Vincent Béringue, Olivier Andréoletti, Didier Vilette
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
R
Q
Online Access:https://doaj.org/article/329de7c6b9af4ceaa86eb3c5f1445ec3
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