White blood cell-based detection of asymptomatic scrapie infection by ex vivo assays.
Prion transmission can occur by blood transfusion in human variant Creutzfeldt-Jakob disease and in experimental animal models, including sheep. Screening of blood and its derivatives for the presence of prions became therefore a major public health issue. As infectious titer in blood is reportedly...
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Main Authors: | Sophie Halliez, Emilie Jaumain, Alvina Huor, Jean-Yves Douet, Séverine Lugan, Hervé Cassard, Caroline Lacroux, Vincent Béringue, Olivier Andréoletti, Didier Vilette |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Subjects: | |
Online Access: | https://doaj.org/article/329de7c6b9af4ceaa86eb3c5f1445ec3 |
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