Early antiinflammatory therapy attenuates brain damage after sah in rats

Early inflammatory processes may play an important role in the development of early brain injury (EBI) after subarachnoid hemorrhage (SAH). Experimental studies suggest that anti-inflammatory and membrane-stabilizing drugs might have beneficial effects, although the underlying mechanisms are not ful...

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Autores principales:	Vadokas Georg, Koehler Stefan, Weiland Judith, Lilla Nadine, Stetter Christian, Westermaier Thomas
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2019
Materias:	subarachnoid hemorrhage early brain injury methylprednisolone minocycline neuroprotection Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Acceso en línea:	https://doaj.org/article/32a92fd4b3ca47faad48fac7b8e4d207
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spelling	oai:doaj.org-article:32a92fd4b3ca47faad48fac7b8e4d2072021-12-05T14:11:04ZEarly antiinflammatory therapy attenuates brain damage after sah in rats2081-693610.1515/tnsci-2019-0018https://doaj.org/article/32a92fd4b3ca47faad48fac7b8e4d2072019-04-01T00:00:00Zhttps://doi.org/10.1515/tnsci-2019-0018https://doaj.org/toc/2081-6936Early inflammatory processes may play an important role in the development of early brain injury (EBI) after subarachnoid hemorrhage (SAH). Experimental studies suggest that anti-inflammatory and membrane-stabilizing drugs might have beneficial effects, although the underlying mechanisms are not fully understood. The aim of this study was to investigate the effect of early treatment with methylprednisolone and minocycline on cerebral perfusion and EBI after experimental SAH.Vadokas GeorgKoehler StefanWeiland JudithLilla NadineStetter ChristianWestermaier ThomasDe Gruyterarticlesubarachnoid hemorrhageearly brain injurymethylprednisoloneminocyclineneuroprotectionNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENTranslational Neuroscience, Vol 10, Iss 1, Pp 104-111 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	subarachnoid hemorrhage early brain injury methylprednisolone minocycline neuroprotection Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
spellingShingle	subarachnoid hemorrhage early brain injury methylprednisolone minocycline neuroprotection Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Vadokas Georg Koehler Stefan Weiland Judith Lilla Nadine Stetter Christian Westermaier Thomas Early antiinflammatory therapy attenuates brain damage after sah in rats
description	Early inflammatory processes may play an important role in the development of early brain injury (EBI) after subarachnoid hemorrhage (SAH). Experimental studies suggest that anti-inflammatory and membrane-stabilizing drugs might have beneficial effects, although the underlying mechanisms are not fully understood. The aim of this study was to investigate the effect of early treatment with methylprednisolone and minocycline on cerebral perfusion and EBI after experimental SAH.
format	article
author	Vadokas Georg Koehler Stefan Weiland Judith Lilla Nadine Stetter Christian Westermaier Thomas
author_facet	Vadokas Georg Koehler Stefan Weiland Judith Lilla Nadine Stetter Christian Westermaier Thomas
author_sort	Vadokas Georg
title	Early antiinflammatory therapy attenuates brain damage after sah in rats
title_short	Early antiinflammatory therapy attenuates brain damage after sah in rats
title_full	Early antiinflammatory therapy attenuates brain damage after sah in rats
title_fullStr	Early antiinflammatory therapy attenuates brain damage after sah in rats
title_full_unstemmed	Early antiinflammatory therapy attenuates brain damage after sah in rats
title_sort	early antiinflammatory therapy attenuates brain damage after sah in rats
publisher	De Gruyter
publishDate	2019
url	https://doaj.org/article/32a92fd4b3ca47faad48fac7b8e4d207
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Early antiinflammatory therapy attenuates brain damage after sah in rats

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