Unwinding of a DNA replication fork by a hexameric viral helicase
Replicative hexameric helicases are fundamental components of replisomes. Here the authors resolve a cryo-EM structure of the E1 helicase from papillomavirus bound to a DNA replication fork, providing insights into the mechanism of DNA unwinding by these hexameric enzymes.
Guardado en:
Autores principales: | Abid Javed, Balazs Major, Jonathan A. Stead, Cyril M. Sanders, Elena V. Orlova |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/32ab17c170964352825d558a35b79273 |
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