Mid-Term Evaluation of iStent Inject® Trabecular Micro-Bypass Stent Implantation with or without Phacoemulsification: A Retrospective Study

Mid-Term Evaluation of iStent Inject® Trabecular Micro-Bypass Stent Implantation with or without Phacoemulsification: A Retrospective Study

Regina Cele Silveira Seixas,1 Marcos Balbino,2 Alberto Basile Neto,3 Amanda de Alcantara Almeida Costa,4 Marcelo Lopes da Silva Jordão,5 Heloisa Helena Abil Russ6 1HCloe Oftalmologia Especializada, Universidade Federal de São Paulo, São Paulo, SP, Brazil; 2HCloe Ofta...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Silveira Seixas RC, Balbino M, Basile Neto A, de Alcantara Almeida Costa A, Jordão MLS, Russ HHA
Format: article
Langue:EN
Publié: Dove Medical Press 2020
Sujets:
glaucoma
medical treatment
trabecular micro-bypass
glaucoma surgery combined with cataract surgery
micro-invasive glaucoma surgery
Ophthalmology
RE1-994
Accès en ligne:https://doaj.org/article/32abd9fbc6a14d27a18e433f36430e7d
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
id oai:doaj.org-article:32abd9fbc6a14d27a18e433f36430e7d
record_format dspace
spelling oai:doaj.org-article:32abd9fbc6a14d27a18e433f36430e7d2021-12-02T16:18:34ZMid-Term Evaluation of iStent Inject® Trabecular Micro-Bypass Stent Implantation with or without Phacoemulsification: A Retrospective Study1177-5483https://doaj.org/article/32abd9fbc6a14d27a18e433f36430e7d2020-12-01T00:00:00Zhttps://www.dovepress.com/mid-term-evaluation-of-istent-injectreg-trabecular-micro-bypass-stent--peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Regina Cele Silveira Seixas,1 Marcos Balbino,2 Alberto Basile Neto,3 Amanda de Alcantara Almeida Costa,4 Marcelo Lopes da Silva Jordão,5 Heloisa Helena Abil Russ6 1HCloe Oftalmologia Especializada, Universidade Federal de São Paulo, São Paulo, SP, Brazil; 2HCloe Oftalmologia Especializada, Centro Universitário São Camilo, São Paulo, SP, Brazil; 3Clínica Oftalmológica do Complexo Hospitalar Padre Bento de Guarulhos, Guarulhos, SP, Brazil; 4Clínica Oftalmológica do Complexo Hospitalar Padre Bento de Guarulhos, Guarulhos, Universidade Estadual de Campinas, Campinas, SP, Brazil; 5Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto Medical School, Universidade de São Paulo, Ribeirão Preto, Brazil; 6HR Oftalmologia, Universidade Federal do Paraná, Curitiba, PR, BrazilCorrespondence: Marcos BalbinoHCloe Oftalmologia Especializada, Centro Universitário São Camilo, Cipriano Barata 1869 Ap. 93, São Paulo, SP, BrazilTel +55 11983462354Email marcosbalbino@mac.comIntroduction: This study evaluated the 6-month performance and safety of micro-invasive glaucoma surgery (MIGS) with iStent inject either with or without cataract surgery.Material and Methods: Longitudinal retrospective study of 86 surgeries in 49 patients with inadequately controlled open-angle glaucoma (OAG) or ocular hypertension who underwent iStent inject trabecular micro-bypass implantation either alone (isolated group) or combined with cataract surgery (combined group). The two primary outcomes included an intraocular pressure (IOP) drop of ≥ 20% versus preoperative values (adequate drop) and IOP maintenance between 6 and 18 mmHg (adequate Range). For both outcomes, we determined “complete” and “qualified” success if patients did not require or did require glaucoma medications, respectively, at the end of follow-up. Safety outcomes included best-corrected visual acuity, adverse events, and secondary surgeries.Results: In the adequate drop analysis, 30.2% achieved “complete success,” and 37.2% achieved “qualified success.” For adequate range, 40.7% achieved “complete success” and 39.5% achieved “qualified success.” There was no difference in medication decrease (p=0.77) nor IOP reduction (p=0.46) between the isolated and combined groups. Safety was generally favorable and similar between groups, with mild transient adverse events that resulted in no sequelae.Discussion/Conclusion: iStent inject implantation either with or without cataract surgery was able to safely decrease IOP and medication requirements through 6 months after surgery.Keywords: glaucoma, medical treatment, trabecular micro-bypass, glaucoma surgery combined with cataract surgery, micro-invasive glaucoma surgerySilveira Seixas RCBalbino MBasile Neto Ade Alcantara Almeida Costa AJordão MLSRuss HHADove Medical Pressarticleglaucomamedical treatmenttrabecular micro-bypassglaucoma surgery combined with cataract surgerymicro-invasive glaucoma surgeryOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 4403-4413 (2020)
institution DOAJ
collection DOAJ
language EN
topic glaucoma
medical treatment
trabecular micro-bypass
glaucoma surgery combined with cataract surgery
micro-invasive glaucoma surgery
Ophthalmology
RE1-994
spellingShingle glaucoma
medical treatment
trabecular micro-bypass
glaucoma surgery combined with cataract surgery
micro-invasive glaucoma surgery
Ophthalmology
RE1-994
Silveira Seixas RC
Balbino M
Basile Neto A
de Alcantara Almeida Costa A
Jordão MLS
Russ HHA
Mid-Term Evaluation of iStent Inject® Trabecular Micro-Bypass Stent Implantation with or without Phacoemulsification: A Retrospective Study
description Regina Cele Silveira Seixas,1 Marcos Balbino,2 Alberto Basile Neto,3 Amanda de Alcantara Almeida Costa,4 Marcelo Lopes da Silva Jordão,5 Heloisa Helena Abil Russ6 1HCloe Oftalmologia Especializada, Universidade Federal de São Paulo, São Paulo, SP, Brazil; 2HCloe Oftalmologia Especializada, Centro Universitário São Camilo, São Paulo, SP, Brazil; 3Clínica Oftalmológica do Complexo Hospitalar Padre Bento de Guarulhos, Guarulhos, SP, Brazil; 4Clínica Oftalmológica do Complexo Hospitalar Padre Bento de Guarulhos, Guarulhos, Universidade Estadual de Campinas, Campinas, SP, Brazil; 5Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto Medical School, Universidade de São Paulo, Ribeirão Preto, Brazil; 6HR Oftalmologia, Universidade Federal do Paraná, Curitiba, PR, BrazilCorrespondence: Marcos BalbinoHCloe Oftalmologia Especializada, Centro Universitário São Camilo, Cipriano Barata 1869 Ap. 93, São Paulo, SP, BrazilTel +55 11983462354Email marcosbalbino@mac.comIntroduction: This study evaluated the 6-month performance and safety of micro-invasive glaucoma surgery (MIGS) with iStent inject either with or without cataract surgery.Material and Methods: Longitudinal retrospective study of 86 surgeries in 49 patients with inadequately controlled open-angle glaucoma (OAG) or ocular hypertension who underwent iStent inject trabecular micro-bypass implantation either alone (isolated group) or combined with cataract surgery (combined group). The two primary outcomes included an intraocular pressure (IOP) drop of ≥ 20% versus preoperative values (adequate drop) and IOP maintenance between 6 and 18 mmHg (adequate Range). For both outcomes, we determined “complete” and “qualified” success if patients did not require or did require glaucoma medications, respectively, at the end of follow-up. Safety outcomes included best-corrected visual acuity, adverse events, and secondary surgeries.Results: In the adequate drop analysis, 30.2% achieved “complete success,” and 37.2% achieved “qualified success.” For adequate range, 40.7% achieved “complete success” and 39.5% achieved “qualified success.” There was no difference in medication decrease (p=0.77) nor IOP reduction (p=0.46) between the isolated and combined groups. Safety was generally favorable and similar between groups, with mild transient adverse events that resulted in no sequelae.Discussion/Conclusion: iStent inject implantation either with or without cataract surgery was able to safely decrease IOP and medication requirements through 6 months after surgery.Keywords: glaucoma, medical treatment, trabecular micro-bypass, glaucoma surgery combined with cataract surgery, micro-invasive glaucoma surgery
format article
author Silveira Seixas RC
Balbino M
Basile Neto A
de Alcantara Almeida Costa A
Jordão MLS
Russ HHA
author_facet Silveira Seixas RC
Balbino M
Basile Neto A
de Alcantara Almeida Costa A
Jordão MLS
Russ HHA
author_sort Silveira Seixas RC
title Mid-Term Evaluation of iStent Inject® Trabecular Micro-Bypass Stent Implantation with or without Phacoemulsification: A Retrospective Study
title_short Mid-Term Evaluation of iStent Inject® Trabecular Micro-Bypass Stent Implantation with or without Phacoemulsification: A Retrospective Study
title_full Mid-Term Evaluation of iStent Inject® Trabecular Micro-Bypass Stent Implantation with or without Phacoemulsification: A Retrospective Study
title_fullStr Mid-Term Evaluation of iStent Inject® Trabecular Micro-Bypass Stent Implantation with or without Phacoemulsification: A Retrospective Study
title_full_unstemmed Mid-Term Evaluation of iStent Inject® Trabecular Micro-Bypass Stent Implantation with or without Phacoemulsification: A Retrospective Study
title_sort mid-term evaluation of istent inject® trabecular micro-bypass stent implantation with or without phacoemulsification: a retrospective study
publisher Dove Medical Press
publishDate 2020
url https://doaj.org/article/32abd9fbc6a14d27a18e433f36430e7d
work_keys_str_mv AT silveiraseixasrc midtermevaluationofistentinjectregtrabecularmicrobypassstentimplantationwithorwithoutphacoemulsificationaretrospectivestudy
AT balbinom midtermevaluationofistentinjectregtrabecularmicrobypassstentimplantationwithorwithoutphacoemulsificationaretrospectivestudy
AT basilenetoa midtermevaluationofistentinjectregtrabecularmicrobypassstentimplantationwithorwithoutphacoemulsificationaretrospectivestudy
AT dealcantaraalmeidacostaa midtermevaluationofistentinjectregtrabecularmicrobypassstentimplantationwithorwithoutphacoemulsificationaretrospectivestudy
AT jordaomls midtermevaluationofistentinjectregtrabecularmicrobypassstentimplantationwithorwithoutphacoemulsificationaretrospectivestudy
AT russhha midtermevaluationofistentinjectregtrabecularmicrobypassstentimplantationwithorwithoutphacoemulsificationaretrospectivestudy
_version_ 1718384162429206528

Documents similaires