Differences in Sleep Disorders between HIV-Infected Persons and Matched Controls with Sleep Problems: A Matched-Cohort Study Based on Laboratory and Survey Data

Objectives: Sleep disturbances are prevalent problems among human immunodeficiency virus (HIV)-infected persons. The recognition of comorbid sleep disorders in patients with HIV is currently hampered by limited knowledge of sleep-related symptoms, sleep architecture, and types of sleep disorders in...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yen-Chin Chen, Chang-Chun Chen, Patrick J. Strollo, Chung-Yi Li, Wen-Chien Ko, Cheng-Yu Lin, Nai-Ying Ko
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	HIV sleep disorders matched controls sleep-disordered breathing psychological disturbances rapid eye movement behavior disorder Medicine R
Acceso en línea:	https://doaj.org/article/32c6105352904ece9f02a22560ac4999
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:32c6105352904ece9f02a22560ac4999
record_format	dspace
spelling	oai:doaj.org-article:32c6105352904ece9f02a22560ac49992021-11-11T17:48:50ZDifferences in Sleep Disorders between HIV-Infected Persons and Matched Controls with Sleep Problems: A Matched-Cohort Study Based on Laboratory and Survey Data10.3390/jcm102152062077-0383https://doaj.org/article/32c6105352904ece9f02a22560ac49992021-11-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/21/5206https://doaj.org/toc/2077-0383Objectives: Sleep disturbances are prevalent problems among human immunodeficiency virus (HIV)-infected persons. The recognition of comorbid sleep disorders in patients with HIV is currently hampered by limited knowledge of sleep-related symptoms, sleep architecture, and types of sleep disorders in this population. We aimed to compare the differences in sleep-related symptoms and polysomnography-based sleep disorders between HIV-infected persons and controls. Methods: The study evaluated 170 men with a Pittsburgh sleep quality index scores greater than 5, including 44 HIV-infected men and 126 male controls who were frequency-matched by sex, age (±3.0 years) and BMI (±3.0 kg/m<sup>2</sup>). For all participants, an overnight sleep study using a Somte V1 monitor was conducted. Differences in sleep-related symptoms and sleep disorders between HIV-infected patients and controls were examined using t-tests or chi-square tests. Results: HIV-infected persons with sleep disturbances more often had psychological disturbances (72.7% vs. 40.5%, <i>p</i> < 0.001) and suspected rapid eye movement behavior disorder (25.0% vs. 4.8%, <i>p</i> < 0.01) than controls. Sleep-disordered breathing was less common in HIV-infected persons than in controls (56.8% vs. 87.3%, <i>p</i> < 0.001). The mean percentage of rapid eye movement sleep was higher among HIV-infected patients than among controls (20.6% vs. 16.6%, <i>p</i> < 0.001). Nocturia was more common in HIV-infected persons than in controls (40.9% vs. 22.2%, <i>p</i> = 0.02). Conclusions: Psychological disturbances and sleep-disordered breathing can be possible explanations of sleep disturbances in HIV-infected persons in whom sleep-disordered breathing is notable. Further studies are warranted to examine the underlying factors of rapid eye movement behavior disorder among HIV-infected persons with sleep disturbances.Yen-Chin ChenChang-Chun ChenPatrick J. StrolloChung-Yi LiWen-Chien KoCheng-Yu LinNai-Ying KoMDPI AGarticleHIVsleep disordersmatched controlssleep-disordered breathingpsychological disturbancesrapid eye movement behavior disorderMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5206, p 5206 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	HIV sleep disorders matched controls sleep-disordered breathing psychological disturbances rapid eye movement behavior disorder Medicine R
spellingShingle	HIV sleep disorders matched controls sleep-disordered breathing psychological disturbances rapid eye movement behavior disorder Medicine R Yen-Chin Chen Chang-Chun Chen Patrick J. Strollo Chung-Yi Li Wen-Chien Ko Cheng-Yu Lin Nai-Ying Ko Differences in Sleep Disorders between HIV-Infected Persons and Matched Controls with Sleep Problems: A Matched-Cohort Study Based on Laboratory and Survey Data
description	Objectives: Sleep disturbances are prevalent problems among human immunodeficiency virus (HIV)-infected persons. The recognition of comorbid sleep disorders in patients with HIV is currently hampered by limited knowledge of sleep-related symptoms, sleep architecture, and types of sleep disorders in this population. We aimed to compare the differences in sleep-related symptoms and polysomnography-based sleep disorders between HIV-infected persons and controls. Methods: The study evaluated 170 men with a Pittsburgh sleep quality index scores greater than 5, including 44 HIV-infected men and 126 male controls who were frequency-matched by sex, age (±3.0 years) and BMI (±3.0 kg/m<sup>2</sup>). For all participants, an overnight sleep study using a Somte V1 monitor was conducted. Differences in sleep-related symptoms and sleep disorders between HIV-infected patients and controls were examined using t-tests or chi-square tests. Results: HIV-infected persons with sleep disturbances more often had psychological disturbances (72.7% vs. 40.5%, <i>p</i> < 0.001) and suspected rapid eye movement behavior disorder (25.0% vs. 4.8%, <i>p</i> < 0.01) than controls. Sleep-disordered breathing was less common in HIV-infected persons than in controls (56.8% vs. 87.3%, <i>p</i> < 0.001). The mean percentage of rapid eye movement sleep was higher among HIV-infected patients than among controls (20.6% vs. 16.6%, <i>p</i> < 0.001). Nocturia was more common in HIV-infected persons than in controls (40.9% vs. 22.2%, <i>p</i> = 0.02). Conclusions: Psychological disturbances and sleep-disordered breathing can be possible explanations of sleep disturbances in HIV-infected persons in whom sleep-disordered breathing is notable. Further studies are warranted to examine the underlying factors of rapid eye movement behavior disorder among HIV-infected persons with sleep disturbances.
format	article
author	Yen-Chin Chen Chang-Chun Chen Patrick J. Strollo Chung-Yi Li Wen-Chien Ko Cheng-Yu Lin Nai-Ying Ko
author_facet	Yen-Chin Chen Chang-Chun Chen Patrick J. Strollo Chung-Yi Li Wen-Chien Ko Cheng-Yu Lin Nai-Ying Ko
author_sort	Yen-Chin Chen
title	Differences in Sleep Disorders between HIV-Infected Persons and Matched Controls with Sleep Problems: A Matched-Cohort Study Based on Laboratory and Survey Data
title_short	Differences in Sleep Disorders between HIV-Infected Persons and Matched Controls with Sleep Problems: A Matched-Cohort Study Based on Laboratory and Survey Data
title_full	Differences in Sleep Disorders between HIV-Infected Persons and Matched Controls with Sleep Problems: A Matched-Cohort Study Based on Laboratory and Survey Data
title_fullStr	Differences in Sleep Disorders between HIV-Infected Persons and Matched Controls with Sleep Problems: A Matched-Cohort Study Based on Laboratory and Survey Data
title_full_unstemmed	Differences in Sleep Disorders between HIV-Infected Persons and Matched Controls with Sleep Problems: A Matched-Cohort Study Based on Laboratory and Survey Data
title_sort	differences in sleep disorders between hiv-infected persons and matched controls with sleep problems: a matched-cohort study based on laboratory and survey data
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/32c6105352904ece9f02a22560ac4999
work_keys_str_mv	AT yenchinchen differencesinsleepdisordersbetweenhivinfectedpersonsandmatchedcontrolswithsleepproblemsamatchedcohortstudybasedonlaboratoryandsurveydata AT changchunchen differencesinsleepdisordersbetweenhivinfectedpersonsandmatchedcontrolswithsleepproblemsamatchedcohortstudybasedonlaboratoryandsurveydata AT patrickjstrollo differencesinsleepdisordersbetweenhivinfectedpersonsandmatchedcontrolswithsleepproblemsamatchedcohortstudybasedonlaboratoryandsurveydata AT chungyili differencesinsleepdisordersbetweenhivinfectedpersonsandmatchedcontrolswithsleepproblemsamatchedcohortstudybasedonlaboratoryandsurveydata AT wenchienko differencesinsleepdisordersbetweenhivinfectedpersonsandmatchedcontrolswithsleepproblemsamatchedcohortstudybasedonlaboratoryandsurveydata AT chengyulin differencesinsleepdisordersbetweenhivinfectedpersonsandmatchedcontrolswithsleepproblemsamatchedcohortstudybasedonlaboratoryandsurveydata AT naiyingko differencesinsleepdisordersbetweenhivinfectedpersonsandmatchedcontrolswithsleepproblemsamatchedcohortstudybasedonlaboratoryandsurveydata
_version_	1718431994399948800

Differences in Sleep Disorders between HIV-Infected Persons and Matched Controls with Sleep Problems: A Matched-Cohort Study Based on Laboratory and Survey Data

Ejemplares similares