Prescription for psychiatric patients in a Brazilian public hospital: cross-sectional study

Background: The growing use of psychotropic drugs has been attributed to a higher frequency of psychiatric disorders diagnosed, interaction of new drugs on the pharmaceutical market, and new therapeutic indications of existing drugs. Given this scenario, the adequacy of the use of psychotropic drug...

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Autores principales:	Maria R. Fernandes, Laura J. Lopes, Milla P. Rocha, Laís P. Almeida, Tânia R. Ferreira, Carolina B. Rogerio, Cristiane C. Bergamaschi
Formato:	article
Lenguaje:	EN PT
Publicado:	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde 2020
Materias:	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/32d2f63298cf4395b0e91ecdba8fc07a
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spelling	oai:doaj.org-article:32d2f63298cf4395b0e91ecdba8fc07a2021-11-28T02:46:04ZPrescription for psychiatric patients in a Brazilian public hospital: cross-sectional study10.30968/rbfhss.2019.104.03622179-59242316-7750https://doaj.org/article/32d2f63298cf4395b0e91ecdba8fc07a2020-03-01T00:00:00Zhttps://www.rbfhss.org.br/sbrafh/article/view/362https://doaj.org/toc/2179-5924https://doaj.org/toc/2316-7750 Background: The growing use of psychotropic drugs has been attributed to a higher frequency of psychiatric disorders diagnosed, interaction of new drugs on the pharmaceutical market, and new therapeutic indications of existing drugs. Given this scenario, the adequacy of the use of psychotropic drugs needs to be analyzed considering the scientific evidences. Objectives: To assess the appropriateness of drug prescriptions used by psychiatric patients in a public hospital in Sorocaba, according to the best available scientific evidence, and to describe the profile of this population. Methods: This cross-sectional study collected data from clinical records of patients with psychiatric disorders hospitalized in the psychiatric sector of the Sorocaba Hospital Complex, state of São Paulo, Brazil, between August 2015 and December 2016. The outcomes measured were: inappropriate use, presence of contraindication and serious or contraindicated drug interactions, according to the information available on the Dynamed® and Micromedex® 2.0 databases. Results: Patients were predominantly adults, and diagnosed with paranoid schizophrenia or bipolar affective disorder. Antipsychotics, benzodiazepines, and lithium accounted for 84.0% (n=2,938) of the 3,500 drugs prescribed for mental disorders. There were 2,157 (61.6%) inappropriate prescriptions, of which 81.9% corresponded to antipsychotics, benzodiazepines, and lithium. There were 1,712 prescriptions with drug combinations that risked causing drug interactions, predominantly involving antipsychotic use (67.0%). Conclusion: The study revealed a high number of inappropriate prescriptions, pointing to a need for greater prescription adequacy to ensure effective safe treatment for psychiatric patients. Maria R. FernandesLaura J. LopesMilla P. RochaLaís P. AlmeidaTânia R. FerreiraCarolina B. RogerioCristiane C. BergamaschiSociedade Brasileira de Farmácia Hospitalar e Serviços de SaúdearticlePublic aspects of medicineRA1-1270Pharmacy and materia medicaRS1-441Therapeutics. PharmacologyRM1-950ENPTRevista Brasileira de Farmácia Hospitalar e Serviços de Saúde, Vol 10, Iss 4 (2020)
institution	DOAJ
collection	DOAJ
language	EN PT
topic	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
spellingShingle	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950 Maria R. Fernandes Laura J. Lopes Milla P. Rocha Laís P. Almeida Tânia R. Ferreira Carolina B. Rogerio Cristiane C. Bergamaschi Prescription for psychiatric patients in a Brazilian public hospital: cross-sectional study
description	Background: The growing use of psychotropic drugs has been attributed to a higher frequency of psychiatric disorders diagnosed, interaction of new drugs on the pharmaceutical market, and new therapeutic indications of existing drugs. Given this scenario, the adequacy of the use of psychotropic drugs needs to be analyzed considering the scientific evidences. Objectives: To assess the appropriateness of drug prescriptions used by psychiatric patients in a public hospital in Sorocaba, according to the best available scientific evidence, and to describe the profile of this population. Methods: This cross-sectional study collected data from clinical records of patients with psychiatric disorders hospitalized in the psychiatric sector of the Sorocaba Hospital Complex, state of São Paulo, Brazil, between August 2015 and December 2016. The outcomes measured were: inappropriate use, presence of contraindication and serious or contraindicated drug interactions, according to the information available on the Dynamed® and Micromedex® 2.0 databases. Results: Patients were predominantly adults, and diagnosed with paranoid schizophrenia or bipolar affective disorder. Antipsychotics, benzodiazepines, and lithium accounted for 84.0% (n=2,938) of the 3,500 drugs prescribed for mental disorders. There were 2,157 (61.6%) inappropriate prescriptions, of which 81.9% corresponded to antipsychotics, benzodiazepines, and lithium. There were 1,712 prescriptions with drug combinations that risked causing drug interactions, predominantly involving antipsychotic use (67.0%). Conclusion: The study revealed a high number of inappropriate prescriptions, pointing to a need for greater prescription adequacy to ensure effective safe treatment for psychiatric patients.
format	article
author	Maria R. Fernandes Laura J. Lopes Milla P. Rocha Laís P. Almeida Tânia R. Ferreira Carolina B. Rogerio Cristiane C. Bergamaschi
author_facet	Maria R. Fernandes Laura J. Lopes Milla P. Rocha Laís P. Almeida Tânia R. Ferreira Carolina B. Rogerio Cristiane C. Bergamaschi
author_sort	Maria R. Fernandes
title	Prescription for psychiatric patients in a Brazilian public hospital: cross-sectional study
title_short	Prescription for psychiatric patients in a Brazilian public hospital: cross-sectional study
title_full	Prescription for psychiatric patients in a Brazilian public hospital: cross-sectional study
title_fullStr	Prescription for psychiatric patients in a Brazilian public hospital: cross-sectional study
title_full_unstemmed	Prescription for psychiatric patients in a Brazilian public hospital: cross-sectional study
title_sort	prescription for psychiatric patients in a brazilian public hospital: cross-sectional study
publisher	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde
publishDate	2020
url	https://doaj.org/article/32d2f63298cf4395b0e91ecdba8fc07a
work_keys_str_mv	AT mariarfernandes prescriptionforpsychiatricpatientsinabrazilianpublichospitalcrosssectionalstudy AT laurajlopes prescriptionforpsychiatricpatientsinabrazilianpublichospitalcrosssectionalstudy AT millaprocha prescriptionforpsychiatricpatientsinabrazilianpublichospitalcrosssectionalstudy AT laispalmeida prescriptionforpsychiatricpatientsinabrazilianpublichospitalcrosssectionalstudy AT taniarferreira prescriptionforpsychiatricpatientsinabrazilianpublichospitalcrosssectionalstudy AT carolinabrogerio prescriptionforpsychiatricpatientsinabrazilianpublichospitalcrosssectionalstudy AT cristianecbergamaschi prescriptionforpsychiatricpatientsinabrazilianpublichospitalcrosssectionalstudy
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Prescription for psychiatric patients in a Brazilian public hospital: cross-sectional study

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