Microbial production of multiple short-chain primary amines via retrobiosynthesis

Short-chain primary amines (SCPAs) are industrially important compounds that are commonly produced under harsh synthetic conditions. Here, the authors report a combination of retrobiosynthesis and precursor selection step for design of biosynthetic pathways leading to production of SCPAs, using vali...

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Autores principales:	Dong In Kim, Tong Un Chae, Hyun Uk Kim, Woo Dae Jang, Sang Yup Lee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/32d66edf5f7942ffa1b16411ff46ebd4
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spelling	oai:doaj.org-article:32d66edf5f7942ffa1b16411ff46ebd42021-12-02T15:16:22ZMicrobial production of multiple short-chain primary amines via retrobiosynthesis10.1038/s41467-020-20423-62041-1723https://doaj.org/article/32d66edf5f7942ffa1b16411ff46ebd42021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20423-6https://doaj.org/toc/2041-1723Short-chain primary amines (SCPAs) are industrially important compounds that are commonly produced under harsh synthetic conditions. Here, the authors report a combination of retrobiosynthesis and precursor selection step for design of biosynthetic pathways leading to production of SCPAs, using valine decarboxylase-expressing Escherichia coli strains.Dong In KimTong Un ChaeHyun Uk KimWoo Dae JangSang Yup LeeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Dong In Kim Tong Un Chae Hyun Uk Kim Woo Dae Jang Sang Yup Lee Microbial production of multiple short-chain primary amines via retrobiosynthesis
description	Short-chain primary amines (SCPAs) are industrially important compounds that are commonly produced under harsh synthetic conditions. Here, the authors report a combination of retrobiosynthesis and precursor selection step for design of biosynthetic pathways leading to production of SCPAs, using valine decarboxylase-expressing Escherichia coli strains.
format	article
author	Dong In Kim Tong Un Chae Hyun Uk Kim Woo Dae Jang Sang Yup Lee
author_facet	Dong In Kim Tong Un Chae Hyun Uk Kim Woo Dae Jang Sang Yup Lee
author_sort	Dong In Kim
title	Microbial production of multiple short-chain primary amines via retrobiosynthesis
title_short	Microbial production of multiple short-chain primary amines via retrobiosynthesis
title_full	Microbial production of multiple short-chain primary amines via retrobiosynthesis
title_fullStr	Microbial production of multiple short-chain primary amines via retrobiosynthesis
title_full_unstemmed	Microbial production of multiple short-chain primary amines via retrobiosynthesis
title_sort	microbial production of multiple short-chain primary amines via retrobiosynthesis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/32d66edf5f7942ffa1b16411ff46ebd4
work_keys_str_mv	AT donginkim microbialproductionofmultipleshortchainprimaryaminesviaretrobiosynthesis AT tongunchae microbialproductionofmultipleshortchainprimaryaminesviaretrobiosynthesis AT hyunukkim microbialproductionofmultipleshortchainprimaryaminesviaretrobiosynthesis AT woodaejang microbialproductionofmultipleshortchainprimaryaminesviaretrobiosynthesis AT sangyuplee microbialproductionofmultipleshortchainprimaryaminesviaretrobiosynthesis
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Microbial production of multiple short-chain primary amines via retrobiosynthesis

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