Crystal structures of APOBEC3G N-domain alone and its complex with DNA
The N-terminal domain of APOBEC3G (A3G) is required for anti-HIV activity, HIV-1 viral infectivity factor (Vif) binds to this domain of A3G to mediate its degradation. Here, the authors use their crystal structures of this A3G domain alone and bound to single-stranded DNA to investigate the molecula...
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Autores principales: | Xiao Xiao, Shu-Xing Li, Hanjing Yang, Xiaojiang S. Chen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/32db43472bcf4a808a00465614aed590 |
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