Crystal structures of APOBEC3G N-domain alone and its complex with DNA

The N-terminal domain of APOBEC3G (A3G) is required for anti-HIV activity, HIV-1 viral infectivity factor (Vif) binds to this domain of A3G to mediate its degradation. Here, the authors use their crystal structures of this A3G domain alone and bound to single-stranded DNA to investigate the molecula...

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Autores principales: Xiao Xiao, Shu-Xing Li, Hanjing Yang, Xiaojiang S. Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/32db43472bcf4a808a00465614aed590
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