CLINICAL AND MORPHOLOGICAL SPECTRUM OF CONGENITAL ANOMALIES OF KIDNEY AND URINARY TRACT (CAKUT) - A TERTIARY CARE CENTER EXPERIENCE

Objective: To determine the type, frequency and clinical presentation of congenital anomalies of kidney and urinary tract in children. Study Design: Cross sectional study. Place and Duration of Study: Pediatric Nephrology Unit of the Children’s Hospital and Institute of Child Health Lahore, fr...

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Autores principales:	Javairia Shakoor, Naureen Akhtar, Shahida Perveen, Ghulam Mujtaba Zafar, Adeela Chaudhry, Farkhanda Hafeez
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2020
Materias:	clinical spectrum congenital anomalies kidney and urinary tract Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/32e50683e6774e91b76074e8e419560d
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spelling	oai:doaj.org-article:32e50683e6774e91b76074e8e419560d2021-12-02T14:55:18ZCLINICAL AND MORPHOLOGICAL SPECTRUM OF CONGENITAL ANOMALIES OF KIDNEY AND URINARY TRACT (CAKUT) - A TERTIARY CARE CENTER EXPERIENCE0030-96482411-8842https://doaj.org/article/32e50683e6774e91b76074e8e419560d2020-10-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/5606https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine the type, frequency and clinical presentation of congenital anomalies of kidney and urinary tract in children. Study Design: Cross sectional study. Place and Duration of Study: Pediatric Nephrology Unit of the Children’s Hospital and Institute of Child Health Lahore, from Mar 2018 to Feb 2019. Methodology: All patients from birth to 18 years of either gender with suspicion of congenital anomalies of kidney and urinary tract presenting to Pediatric Nephrology unit with different clinical manifestation were enrolled for study. All the children were subjected to detailed history and physical examination including age, gender, height, weight and associated anomalies of other systems while screening ultrasound was carried out with other radiological investigations accordingly. Results: One hundred and forty subjects were enrolled in the study with male to female ratio = 3:1. The mean weight and height of children were 13.35 ± 9.35 kg and 89.66 ± 29.95 cm respectively. Total 85 (60.7%) patients were product of consanguineous parents while 12 (8.6%) were premature and 31 (22.1%) were small for gestational age (SGA). There was history of birth asphyxia in 4 (2.9%) subjects while mothers of 6 (4.3%) were diabetic at the time of conception. Patients had diverse clinical presentation - the most common being urinary tract infection (UTI) seen in 67 (47.86%) while 32 (15.7%) subjects had associated anomalies of other systems. Most common primary anomaly was vesicoureteic reflux (VUR) 83 (59.3%). Conclusion: The most common type of congenital anomalies of kidney and urinary tract seen in our patients was vesicoureteic reflux. Majority of children presented in infancy with urinary tract infection being the clinical presentation in two-thirds subjects.Javairia ShakoorNaureen AkhtarShahida PerveenGhulam Mujtaba ZafarAdeela ChaudhryFarkhanda HafeezArmy Medical College Rawalpindiarticleclinical spectrumcongenital anomalieskidney and urinary tractMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 5, Pp 1565-1570 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	clinical spectrum congenital anomalies kidney and urinary tract Medicine R Medicine (General) R5-920
spellingShingle	clinical spectrum congenital anomalies kidney and urinary tract Medicine R Medicine (General) R5-920 Javairia Shakoor Naureen Akhtar Shahida Perveen Ghulam Mujtaba Zafar Adeela Chaudhry Farkhanda Hafeez CLINICAL AND MORPHOLOGICAL SPECTRUM OF CONGENITAL ANOMALIES OF KIDNEY AND URINARY TRACT (CAKUT) - A TERTIARY CARE CENTER EXPERIENCE
description	Objective: To determine the type, frequency and clinical presentation of congenital anomalies of kidney and urinary tract in children. Study Design: Cross sectional study. Place and Duration of Study: Pediatric Nephrology Unit of the Children’s Hospital and Institute of Child Health Lahore, from Mar 2018 to Feb 2019. Methodology: All patients from birth to 18 years of either gender with suspicion of congenital anomalies of kidney and urinary tract presenting to Pediatric Nephrology unit with different clinical manifestation were enrolled for study. All the children were subjected to detailed history and physical examination including age, gender, height, weight and associated anomalies of other systems while screening ultrasound was carried out with other radiological investigations accordingly. Results: One hundred and forty subjects were enrolled in the study with male to female ratio = 3:1. The mean weight and height of children were 13.35 ± 9.35 kg and 89.66 ± 29.95 cm respectively. Total 85 (60.7%) patients were product of consanguineous parents while 12 (8.6%) were premature and 31 (22.1%) were small for gestational age (SGA). There was history of birth asphyxia in 4 (2.9%) subjects while mothers of 6 (4.3%) were diabetic at the time of conception. Patients had diverse clinical presentation - the most common being urinary tract infection (UTI) seen in 67 (47.86%) while 32 (15.7%) subjects had associated anomalies of other systems. Most common primary anomaly was vesicoureteic reflux (VUR) 83 (59.3%). Conclusion: The most common type of congenital anomalies of kidney and urinary tract seen in our patients was vesicoureteic reflux. Majority of children presented in infancy with urinary tract infection being the clinical presentation in two-thirds subjects.
format	article
author	Javairia Shakoor Naureen Akhtar Shahida Perveen Ghulam Mujtaba Zafar Adeela Chaudhry Farkhanda Hafeez
author_facet	Javairia Shakoor Naureen Akhtar Shahida Perveen Ghulam Mujtaba Zafar Adeela Chaudhry Farkhanda Hafeez
author_sort	Javairia Shakoor
title	CLINICAL AND MORPHOLOGICAL SPECTRUM OF CONGENITAL ANOMALIES OF KIDNEY AND URINARY TRACT (CAKUT) - A TERTIARY CARE CENTER EXPERIENCE
title_short	CLINICAL AND MORPHOLOGICAL SPECTRUM OF CONGENITAL ANOMALIES OF KIDNEY AND URINARY TRACT (CAKUT) - A TERTIARY CARE CENTER EXPERIENCE
title_full	CLINICAL AND MORPHOLOGICAL SPECTRUM OF CONGENITAL ANOMALIES OF KIDNEY AND URINARY TRACT (CAKUT) - A TERTIARY CARE CENTER EXPERIENCE
title_fullStr	CLINICAL AND MORPHOLOGICAL SPECTRUM OF CONGENITAL ANOMALIES OF KIDNEY AND URINARY TRACT (CAKUT) - A TERTIARY CARE CENTER EXPERIENCE
title_full_unstemmed	CLINICAL AND MORPHOLOGICAL SPECTRUM OF CONGENITAL ANOMALIES OF KIDNEY AND URINARY TRACT (CAKUT) - A TERTIARY CARE CENTER EXPERIENCE
title_sort	clinical and morphological spectrum of congenital anomalies of kidney and urinary tract (cakut) - a tertiary care center experience
publisher	Army Medical College Rawalpindi
publishDate	2020
url	https://doaj.org/article/32e50683e6774e91b76074e8e419560d
work_keys_str_mv	AT javairiashakoor clinicalandmorphologicalspectrumofcongenitalanomaliesofkidneyandurinarytractcakutatertiarycarecenterexperience AT naureenakhtar clinicalandmorphologicalspectrumofcongenitalanomaliesofkidneyandurinarytractcakutatertiarycarecenterexperience AT shahidaperveen clinicalandmorphologicalspectrumofcongenitalanomaliesofkidneyandurinarytractcakutatertiarycarecenterexperience AT ghulammujtabazafar clinicalandmorphologicalspectrumofcongenitalanomaliesofkidneyandurinarytractcakutatertiarycarecenterexperience AT adeelachaudhry clinicalandmorphologicalspectrumofcongenitalanomaliesofkidneyandurinarytractcakutatertiarycarecenterexperience AT farkhandahafeez clinicalandmorphologicalspectrumofcongenitalanomaliesofkidneyandurinarytractcakutatertiarycarecenterexperience
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CLINICAL AND MORPHOLOGICAL SPECTRUM OF CONGENITAL ANOMALIES OF KIDNEY AND URINARY TRACT (CAKUT) - A TERTIARY CARE CENTER EXPERIENCE

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