Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues
Drug addiction is a chronic disorder and many sufferers experience relapses even after a period of successful abstinence. Here, the authors reveal a subset of neurons in the rat infralimbic cortex that suppresses relapse into cocaine or alcohol use by responding to drug-omission cues.
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Nature Portfolio
2019
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oai:doaj.org-article:32e54db896614f8fb088a7ce1dccb6492021-12-02T14:39:40ZAnti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues10.1038/s41467-019-11799-12041-1723https://doaj.org/article/32e54db896614f8fb088a7ce1dccb6492019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11799-1https://doaj.org/toc/2041-1723Drug addiction is a chronic disorder and many sufferers experience relapses even after a period of successful abstinence. Here, the authors reveal a subset of neurons in the rat infralimbic cortex that suppresses relapse into cocaine or alcohol use by responding to drug-omission cues.Amanda LaqueGenna L. De NessGrant E. WagnerHermina NedelescuAyla CarrollDebbie WatryTony M. KerrEisuke KoyaBruce T. HopeFriedbert WeissGreg I. ElmerNobuyoshi SutoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019) |
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Science Q Amanda Laque Genna L. De Ness Grant E. Wagner Hermina Nedelescu Ayla Carroll Debbie Watry Tony M. Kerr Eisuke Koya Bruce T. Hope Friedbert Weiss Greg I. Elmer Nobuyoshi Suto Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues |
description |
Drug addiction is a chronic disorder and many sufferers experience relapses even after a period of successful abstinence. Here, the authors reveal a subset of neurons in the rat infralimbic cortex that suppresses relapse into cocaine or alcohol use by responding to drug-omission cues. |
format |
article |
author |
Amanda Laque Genna L. De Ness Grant E. Wagner Hermina Nedelescu Ayla Carroll Debbie Watry Tony M. Kerr Eisuke Koya Bruce T. Hope Friedbert Weiss Greg I. Elmer Nobuyoshi Suto |
author_facet |
Amanda Laque Genna L. De Ness Grant E. Wagner Hermina Nedelescu Ayla Carroll Debbie Watry Tony M. Kerr Eisuke Koya Bruce T. Hope Friedbert Weiss Greg I. Elmer Nobuyoshi Suto |
author_sort |
Amanda Laque |
title |
Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues |
title_short |
Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues |
title_full |
Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues |
title_fullStr |
Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues |
title_full_unstemmed |
Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues |
title_sort |
anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/32e54db896614f8fb088a7ce1dccb649 |
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