Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues

Drug addiction is a chronic disorder and many sufferers experience relapses even after a period of successful abstinence. Here, the authors reveal a subset of neurons in the rat infralimbic cortex that suppresses relapse into cocaine or alcohol use by responding to drug-omission cues.

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Autores principales: Amanda Laque, Genna L. De Ness, Grant E. Wagner, Hermina Nedelescu, Ayla Carroll, Debbie Watry, Tony M. Kerr, Eisuke Koya, Bruce T. Hope, Friedbert Weiss, Greg I. Elmer, Nobuyoshi Suto
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/32e54db896614f8fb088a7ce1dccb649
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spelling oai:doaj.org-article:32e54db896614f8fb088a7ce1dccb6492021-12-02T14:39:40ZAnti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues10.1038/s41467-019-11799-12041-1723https://doaj.org/article/32e54db896614f8fb088a7ce1dccb6492019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11799-1https://doaj.org/toc/2041-1723Drug addiction is a chronic disorder and many sufferers experience relapses even after a period of successful abstinence. Here, the authors reveal a subset of neurons in the rat infralimbic cortex that suppresses relapse into cocaine or alcohol use by responding to drug-omission cues.Amanda LaqueGenna L. De NessGrant E. WagnerHermina NedelescuAyla CarrollDebbie WatryTony M. KerrEisuke KoyaBruce T. HopeFriedbert WeissGreg I. ElmerNobuyoshi SutoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Amanda Laque
Genna L. De Ness
Grant E. Wagner
Hermina Nedelescu
Ayla Carroll
Debbie Watry
Tony M. Kerr
Eisuke Koya
Bruce T. Hope
Friedbert Weiss
Greg I. Elmer
Nobuyoshi Suto
Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues
description Drug addiction is a chronic disorder and many sufferers experience relapses even after a period of successful abstinence. Here, the authors reveal a subset of neurons in the rat infralimbic cortex that suppresses relapse into cocaine or alcohol use by responding to drug-omission cues.
format article
author Amanda Laque
Genna L. De Ness
Grant E. Wagner
Hermina Nedelescu
Ayla Carroll
Debbie Watry
Tony M. Kerr
Eisuke Koya
Bruce T. Hope
Friedbert Weiss
Greg I. Elmer
Nobuyoshi Suto
author_facet Amanda Laque
Genna L. De Ness
Grant E. Wagner
Hermina Nedelescu
Ayla Carroll
Debbie Watry
Tony M. Kerr
Eisuke Koya
Bruce T. Hope
Friedbert Weiss
Greg I. Elmer
Nobuyoshi Suto
author_sort Amanda Laque
title Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues
title_short Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues
title_full Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues
title_fullStr Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues
title_full_unstemmed Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues
title_sort anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/32e54db896614f8fb088a7ce1dccb649
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